Melkani GC - Search Results

1

Prolonged cross-bridge binding triggers muscle dysfunction in a Drosophila model of myosin-based hypertrophic cardiomyopathy.

Kronert WA, Bell KM, Viswanathan MC, Melkani GC, Trujillo AS, Huang A, Melkani A, Cammarato A, Swank DM, Bernstein SI. Kronert WA, et al. Among authors: melkani gc, melkani a. Elife. 2018 Aug 13;7:e38064. doi: 10.7554/eLife.38064. Elife. 2018. PMID: 30102150 Free PMC article.

2

A Skeletal Muscle-Centric View on Time-Restricted Feeding and Obesity under Various Metabolic Challenges in Humans and Animals.

Livelo C, Guo Y, Melkani GC. Livelo C, et al. Among authors: melkani gc. Int J Mol Sci. 2022 Dec 27;24(1):422. doi: 10.3390/ijms24010422. Int J Mol Sci. 2022. PMID: 36613864 Free PMC article. Review.

3

alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress.

Melkani GC, Cammarato A, Bernstein SI. Melkani GC, et al. J Mol Biol. 2006 May 5;358(3):635-45. doi: 10.1016/j.jmb.2006.02.043. Epub 2006 Mar 3. J Mol Biol. 2006. PMID: 16546210

4

Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head.

Bloemink MJ, Dambacher CM, Knowles AF, Melkani GC, Geeves MA, Bernstein SI. Bloemink MJ, et al. Among authors: melkani gc. J Mol Biol. 2009 Jun 19;389(4):707-21. doi: 10.1016/j.jmb.2009.04.036. Epub 2009 Apr 22. J Mol Biol. 2009. PMID: 19393244 Free PMC article.

5

Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability.

Kronert WA, Melkani GC, Melkani A, Bernstein SI. Kronert WA, et al. Among authors: melkani gc, melkani a. J Mol Biol. 2010 May 21;398(5):625-32. doi: 10.1016/j.jmb.2010.03.049. Epub 2010 Apr 1. J Mol Biol. 2010. PMID: 20362584 Free PMC article.

6

Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase.

Melkani GC, Lee CF, Cammarato A, Bernstein SI. Melkani GC, et al. Biochem Biophys Res Commun. 2010 May 28;396(2):317-22. doi: 10.1016/j.bbrc.2010.04.090. Epub 2010 Apr 18. Biochem Biophys Res Commun. 2010. PMID: 20403336 Free PMC article.

7

Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability.

Lee CF, Melkani GC, Yu Q, Suggs JA, Kronert WA, Suzuki Y, Hipolito L, Price MG, Epstein HF, Bernstein SI. Lee CF, et al. Among authors: melkani gc. J Cell Sci. 2011 Mar 1;124(Pt 5):699-705. doi: 10.1242/jcs.078964. Epub 2011 Feb 1. J Cell Sci. 2011. PMID: 21285246 Free PMC article.

8

Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities.

Bloemink MJ, Melkani GC, Dambacher CM, Bernstein SI, Geeves MA. Bloemink MJ, et al. Among authors: melkani gc. J Biol Chem. 2011 Aug 12;286(32):28435-43. doi: 10.1074/jbc.M111.258228. Epub 2011 Jun 16. J Biol Chem. 2011. PMID: 21680742 Free PMC article.

9

The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.

Melkani GC, Bodmer R, Ocorr K, Bernstein SI. Melkani GC, et al. PLoS One. 2011;6(7):e22579. doi: 10.1371/journal.pone.0022579. Epub 2011 Jul 25. PLoS One. 2011. PMID: 21799905 Free PMC article.

10

Transgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system.

Caldwell JT, Melkani GC, Huxford T, Bernstein SI. Caldwell JT, et al. Among authors: melkani gc. Methods. 2012 Jan;56(1):25-32. doi: 10.1016/j.ymeth.2011.12.002. Epub 2011 Dec 8. Methods. 2012. PMID: 22178692 Free PMC article.

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