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Comprehensive evaluation of coding region point mutations in microsatellite-unstable colorectal cancer.
Kondelin J, Salokas K, Saarinen L, Ovaska K, Rauanheimo H, Plaketti RM, Hamberg J, Liu X, Yadav L, Gylfe AE, Cajuso T, Hänninen UA, Palin K, Ristolainen H, Katainen R, Kaasinen E, Tanskanen T, Aavikko M, Taipale M, Taipale J, Renkonen-Sinisalo L, Lepistö A, Koskensalo S, Böhm J, Mecklin JP, Ongen H, Dermitzakis ET, Kilpivaara O, Vahteristo P, Turunen M, Hautaniemi S, Tuupanen S, Karhu A, Välimäki N, Varjosalo M, Pitkänen E, Aaltonen LA. Kondelin J, et al. Among authors: ongen h. EMBO Mol Med. 2018 Sep;10(9):e8552. doi: 10.15252/emmm.201708552. EMBO Mol Med. 2018. PMID: 30108113 Free PMC article.
Putative cis-regulatory drivers in colorectal cancer.
Ongen H, Andersen CL, Bramsen JB, Oster B, Rasmussen MH, Ferreira PG, Sandoval J, Vidal E, Whiffin N, Planchon A, Padioleau I, Bielser D, Romano L, Tomlinson I, Houlston RS, Esteller M, Orntoft TF, Dermitzakis ET. Ongen H, et al. Nature. 2014 Aug 7;512(7512):87-90. doi: 10.1038/nature13602. Epub 2014 Jul 23. Nature. 2014. PMID: 25079323
SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism.
Christensen LL, True K, Hamilton MP, Nielsen MM, Damas ND, Damgaard CK, Ongen H, Dermitzakis E, Bramsen JB, Pedersen JS, Lund AH, Vang S, Stribolt K, Madsen MR, Laurberg S, McGuire SE, Ørntoft TF, Andersen CL. Christensen LL, et al. Among authors: ongen h. Mol Oncol. 2016 Oct;10(8):1266-82. doi: 10.1016/j.molonc.2016.06.003. Epub 2016 Jun 26. Mol Oncol. 2016. PMID: 27396952 Free PMC article.
The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression.
Liu NQ, Ter Huurne M, Nguyen LN, Peng T, Wang SY, Studd JB, Joshi O, Ongen H, Bramsen JB, Yan J, Andersen CL, Taipale J, Dermitzakis ET, Houlston RS, Hubner NC, Stunnenberg HG. Liu NQ, et al. Among authors: ongen h. Nat Commun. 2017 Feb 14;8:14418. doi: 10.1038/ncomms14418. Nat Commun. 2017. PMID: 28195176 Free PMC article.
Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer.
Bramsen JB, Rasmussen MH, Ongen H, Mattesen TB, Ørntoft MW, Árnadóttir SS, Sandoval J, Laguna T, Vang S, Øster B, Lamy P, Madsen MR, Laurberg S, Esteller M, Dermitzakis ET, Ørntoft TF, Andersen CL. Bramsen JB, et al. Among authors: ongen h. Cell Rep. 2017 May 9;19(6):1268-1280. doi: 10.1016/j.celrep.2017.04.045. Cell Rep. 2017. PMID: 28494874 Free article.
A complete tool set for molecular QTL discovery and analysis.
Delaneau O, Ongen H, Brown AA, Fort A, Panousis NI, Dermitzakis ET. Delaneau O, et al. Among authors: ongen h. Nat Commun. 2017 May 18;8:15452. doi: 10.1038/ncomms15452. Nat Commun. 2017. PMID: 28516912 Free PMC article.
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