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Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.
Rahrmann EP, Moriarity BS, Otto GM, Watson AL, Choi K, Collins MH, Wallace M, Webber BR, Forster CL, Rizzardi AE, Schmechel SC, Ratner N, Largaespada DA. Rahrmann EP, et al. Among authors: webber br. Am J Pathol. 2014 Jul;184(7):2082-98. doi: 10.1016/j.ajpath.2014.04.006. Epub 2014 May 13. Am J Pathol. 2014. PMID: 24832557 Free PMC article.
Fanconi anemia gene editing by the CRISPR/Cas9 system.
Osborn MJ, Gabriel R, Webber BR, DeFeo AP, McElroy AN, Jarjour J, Starker CG, Wagner JE, Joung JK, Voytas DF, von Kalle C, Schmidt M, Blazar BR, Tolar J. Osborn MJ, et al. Among authors: webber br. Hum Gene Ther. 2015 Feb;26(2):114-26. doi: 10.1089/hum.2014.111. Hum Gene Ther. 2015. PMID: 25545896 Free PMC article.
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases.
Osborn MJ, Webber BR, Knipping F, Lonetree CL, Tennis N, DeFeo AP, McElroy AN, Starker CG, Lee C, Merkel S, Lund TC, Kelly-Spratt KS, Jensen MC, Voytas DF, von Kalle C, Schmidt M, Gabriel R, Hippen KL, Miller JS, Scharenberg AM, Tolar J, Blazar BR. Osborn MJ, et al. Among authors: webber br. Mol Ther. 2016 Mar;24(3):570-81. doi: 10.1038/mt.2015.197. Epub 2015 Oct 27. Mol Ther. 2016. PMID: 26502778 Free PMC article.
Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells.
Webber BR, O'Connor KT, McElmurry RT, Durgin EN, Eide CR, Lees CJ, Riddle MJ, Mathews WE, Frank NY, Kluth MA, Ganss C, Moriarity BS, Frank MH, Osborn MJ, Tolar J. Webber BR, et al. Lab Invest. 2017 Oct;97(10):1218-1224. doi: 10.1038/labinvest.2017.85. Epub 2017 Sep 11. Lab Invest. 2017. PMID: 28892093 Free PMC article.
CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression.
Osborn MJ, Lees CJ, McElroy AN, Merkel SC, Eide CR, Mathews W, Feser CJ, Tschann M, McElmury RT, Webber BR, Kim CJ, Blazar BR, Tolar J. Osborn MJ, et al. Among authors: webber br. Int J Mol Sci. 2018 Mar 22;19(4):946. doi: 10.3390/ijms19040946. Int J Mol Sci. 2018. PMID: 29565806 Free PMC article.
Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays.
Kurata M, Wolf NK, Lahr WS, Weg MT, Kluesner MG, Lee S, Hui K, Shiraiwa M, Webber BR, Moriarity BS. Kurata M, et al. Among authors: webber br. PLoS One. 2018 Sep 17;13(9):e0198714. doi: 10.1371/journal.pone.0198714. eCollection 2018. PLoS One. 2018. PMID: 30222773 Free PMC article.
EditR: A Method to Quantify Base Editing from Sanger Sequencing.
Kluesner MG, Nedveck DA, Lahr WS, Garbe JR, Abrahante JE, Webber BR, Moriarity BS. Kluesner MG, et al. Among authors: webber br. CRISPR J. 2018 Jun;1(3):239-250. doi: 10.1089/crispr.2018.0014. CRISPR J. 2018. PMID: 31021262 Free PMC article.
A Genetically Engineered Primary Human Natural Killer Cell Platform for Cancer Immunotherapy.
Pomeroy EJ, Hunzeker JT, Kluesner MG, Lahr WS, Smeester BA, Crosby MR, Lonetree CL, Yamamoto K, Bendzick L, Miller JS, Geller MA, Walcheck B, Felices M, Webber BR, Starr TK, Moriarity BS. Pomeroy EJ, et al. Among authors: webber br. Mol Ther. 2020 Jan 8;28(1):52-63. doi: 10.1016/j.ymthe.2019.10.009. Epub 2019 Oct 15. Mol Ther. 2020. PMID: 31704085 Free PMC article.
56 results