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Page 1
Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation.
D'Souza AM, Jiang Y, Cast A, Valanejad L, Wright M, Lewis K, Kumbaji M, Shah S, Smithrud D, Karns R, Shin S, Timchenko N. D'Souza AM, et al. Among authors: kumbaji m. Cell Mol Gastroenterol Hepatol. 2018 May 24;6(3):239-255. doi: 10.1016/j.jcmgh.2018.05.007. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30109252 Free PMC article.
HDAC1-Dependent Repression of Markers of Hepatocytes and P21 Is Involved in Development of Pediatric Liver Cancer.
Rivas M, Johnston ME 2nd, Gulati R, Kumbaji M, Margues Aguiar TF, Timchenko L, Krepischi A, Shin S, Bondoc A, Tiao G, Geller J, Timchenko N. Rivas M, et al. Among authors: kumbaji m. Cell Mol Gastroenterol Hepatol. 2021;12(5):1669-1682. doi: 10.1016/j.jcmgh.2021.06.026. Epub 2021 Jul 8. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34245919 Free PMC article.
β-catenin cancer-enhancing genomic regions axis is involved in the development of fibrolamellar hepatocellular carcinoma.
Gulati R, Johnston M, Rivas M, Cast A, Kumbaji M, Hanlon MA, Lee S, Zhou P, Lake C, Schepers E, Min KW, Yoon JH, Karns R, Reid LM, Lopez-Terrada D, Timchenko L, Parameswaran S, Weirauch MT, Ranganathan S, Bondoc A, Geller J, Tiao G, Shin S, Timchenko N. Gulati R, et al. Among authors: kumbaji m. Hepatol Commun. 2022 Oct;6(10):2950-2963. doi: 10.1002/hep4.2055. Epub 2022 Aug 24. Hepatol Commun. 2022. PMID: 36000549 Free PMC article.
Olaparib Inhibits Tumor Growth of Hepatoblastoma in Patient-Derived Xenograft Models.
Johnston ME 2nd, Rivas MP, Nicolle D, Gorse A, Gulati R, Kumbaji M, Weirauch MT, Bondoc A, Cairo S, Geller J, Tiao G, Timchenko N. Johnston ME 2nd, et al. Among authors: kumbaji m. Hepatology. 2021 Oct;74(4):2201-2215. doi: 10.1002/hep.31919. Epub 2021 Aug 10. Hepatology. 2021. PMID: 34037269 Free PMC article.
En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH.
Kimura M, Iguchi T, Iwasawa K, Dunn A, Thompson WL, Yoneyama Y, Chaturvedi P, Zorn AM, Wintzinger M, Quattrocelli M, Watanabe-Chailland M, Zhu G, Fujimoto M, Kumbaji M, Kodaka A, Gindin Y, Chung C, Myers RP, Subramanian GM, Hwa V, Takebe T. Kimura M, et al. Among authors: kumbaji m. Cell. 2022 Oct 27;185(22):4216-4232.e16. doi: 10.1016/j.cell.2022.09.031. Epub 2022 Oct 13. Cell. 2022. PMID: 36240780 Free PMC article.
Genetic causes of growth hormone insensitivity beyond GHR.
Hwa V, Fujimoto M, Zhu G, Gao W, Foley C, Kumbaji M, Rosenfeld RG. Hwa V, et al. Among authors: kumbaji m. Rev Endocr Metab Disord. 2021 Mar;22(1):43-58. doi: 10.1007/s11154-020-09603-3. Epub 2020 Oct 8. Rev Endocr Metab Disord. 2021. PMID: 33029712 Free PMC article. Review.