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Novel isatin-derived molecules activate p53 via interference with Mdm2 to promote apoptosis.
Fedorova O, Daks A, Petrova V, Petukhov A, Lezina L, Shuvalov O, Davidovich P, Kriger D, Lomert E, Tentler D, Kartsev V, Uyanik B, Tribulovich V, Demidov O, Melino G, Barlev NA. Fedorova O, et al. Among authors: demidov o. Cell Cycle. 2018;17(15):1917-1930. doi: 10.1080/15384101.2018.1506664. Epub 2018 Sep 5. Cell Cycle. 2018. PMID: 30109812 Free PMC article.
EMT: A mechanism for escape from EGFR-targeted therapy in lung cancer.
Tulchinsky E, Demidov O, Kriajevska M, Barlev NA, Imyanitov E. Tulchinsky E, et al. Among authors: demidov o. Biochim Biophys Acta Rev Cancer. 2019 Jan;1871(1):29-39. doi: 10.1016/j.bbcan.2018.10.003. Epub 2018 Nov 10. Biochim Biophys Acta Rev Cancer. 2019. PMID: 30419315 Review.
Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy.
Gozzi GJ, Gonzalez D, Boudesco C, Dias AMM, Gotthard G, Uyanik B, Dondaine L, Marcion G, Hermetet F, Denis C, Hardy L, Suzanne P, Douhard R, Jego G, Dubrez L, Demidov ON, Neiers F, Briand L, Sopková-de Oliveira Santos J, Voisin-Chiret AS, Garrido C. Gozzi GJ, et al. Cell Death Differ. 2020 Jan;27(1):117-129. doi: 10.1038/s41418-019-0343-4. Epub 2019 May 8. Cell Death Differ. 2020. PMID: 31068676 Free PMC article.
Transglutaminase Type 2 is Involved in the Hematopoietic Stem Cells Homeostasis.
Oliverio S, Beltran JSO, Occhigrossi L, Bordoni V, Agrati C, D'Eletto M, Rossin F, Borelli P, Amarante-Mendes GP, Demidov O, Barlev NA, Piacentini M. Oliverio S, et al. Among authors: demidov o. Biochemistry (Mosc). 2020 Oct;85(10):1159-1168. doi: 10.1134/S0006297920100041. Biochemistry (Mosc). 2020. PMID: 33202201
Lactobacillus stress protein GroEL prevents colonic inflammation.
Dias AMM, Douhard R, Hermetet F, Regimbeau M, Lopez TE, Gonzalez D, Masson S, Marcion G, Chaumonnot K, Uyanik B, Causse SZ, Rieu A, Hadi T, Basset C, Chluba J, Grober J, Guzzo J, Neiers F, Ortega-Deballon P, Demidov ON, Lirussi F, Garrido C. Dias AMM, et al. J Gastroenterol. 2021 May;56(5):442-455. doi: 10.1007/s00535-021-01774-3. Epub 2021 Mar 29. J Gastroenterol. 2021. PMID: 33782752
Inhibition of the DNA damage response phosphatase PPM1D reprograms neutrophils to enhance anti-tumor immune responses.
Uyanik B, Goloudina AR, Akbarali A, Grigorash BB, Petukhov AV, Singhal S, Eruslanov E, Chaloyard J, Lagorgette L, Hadi T, Baidyuk EV, Sakai H, Tessarollo L, Ryffel B, Mazur SJ, Lirussi F, Garrido C, Appella E, Demidov ON. Uyanik B, et al. Nat Commun. 2021 Jun 15;12(1):3622. doi: 10.1038/s41467-021-23330-6. Nat Commun. 2021. PMID: 34131120 Free PMC article.
81 results