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Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration.
Smith B, Kiessling A, Lledo-Garcia R, Dixon KL, Christodoulou L, Catley MC, Atherfold P, D'Hooghe LE, Finney H, Greenslade K, Hailu H, Kevorkian L, Lightwood D, Meier C, Munro R, Qureshi O, Sarkar K, Shaw SP, Tewari R, Turner A, Tyson K, West S, Shaw S, Brennan FR. Smith B, et al. MAbs. 2018 Oct;10(7):1111-1130. doi: 10.1080/19420862.2018.1505464. Epub 2018 Sep 12. MAbs. 2018. PMID: 30130439 Free PMC article.
The discovery, engineering and characterisation of a highly potent anti-human IL-13 fab fragment designed for administration by inhalation.
Lightwood D, O'Dowd V, Carrington B, Veverka V, Carr MD, Tservistas M, Henry AJ, Smith B, Tyson K, Lamour S, Bracher M, Sarkar K, Turner A, Lawson AD, Bourne T, Gozzard N, Palframan R. Lightwood D, et al. Among authors: smith b. J Mol Biol. 2013 Feb 8;425(3):577-93. doi: 10.1016/j.jmb.2012.11.036. Epub 2012 Dec 3. J Mol Biol. 2013. PMID: 23219467
Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis.
Guptill JT, Juel VC, Massey JM, Anderson AC, Chopra M, Yi JS, Esfandiari E, Buchanan T, Smith B, Atherfold P, Jones E, Howard JF Jr. Guptill JT, et al. Among authors: smith b. Autoimmunity. 2016 Nov;49(7):472-479. doi: 10.1080/08916934.2016.1214823. Epub 2016 Aug 11. Autoimmunity. 2016. PMID: 27684107 Free PMC article.
Efficacy of an Inhaled IL-13 Antibody Fragment in a Model of Chronic Asthma.
Lightwood D, Tservistas M, Zehentleitner M, Sarkar K, Turner A, Bracher M, Smith B, Lamour S, Bourne T, Shaw S, Gozzard N, Palframan RT. Lightwood D, et al. Among authors: smith b. Am J Respir Crit Care Med. 2018 Sep 1;198(5):610-619. doi: 10.1164/rccm.201712-2382OC. Am J Respir Crit Care Med. 2018. PMID: 29883204
Corrigendum to "The Discovery, Engineering and Characterisation of a Highly Potent Anti-Human IL-13 Fab Fragment Designed for Administration by Inhalation" [J. Mol. Biol. 425 (2013), 577-593].
Lightwood D, O'Dowd V, Carrington B, Veverka V, Carr MD, Tservistas M, Henry AJ, Smith B, Tyson K, Lamour S, Bracher M, Sarkar K, Turner A, Lawson AD, Bourne T, Gozzard N, Palframan R. Lightwood D, et al. Among authors: smith b. J Mol Biol. 2013 Jun 12;425(11):2082. doi: 10.1016/j.jmb.2013.03.038. Epub 2013 Apr 5. J Mol Biol. 2013. PMID: 29890570 No abstract available.
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