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Page 1
Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody.
Malito E, Biancucci M, Faleri A, Ferlenghi I, Scarselli M, Maruggi G, Lo Surdo P, Veggi D, Liguori A, Santini L, Bertoldi I, Petracca R, Marchi S, Romagnoli G, Cartocci E, Vercellino I, Savino S, Spraggon G, Norais N, Pizza M, Rappuoli R, Masignani V, Bottomley MJ. Malito E, et al. Among authors: spraggon g. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17128-33. doi: 10.1073/pnas.1419686111. Epub 2014 Nov 17. Proc Natl Acad Sci U S A. 2014. PMID: 25404323 Free PMC article.
Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197.
Malito E, Bursulaya B, Chen C, Lo Surdo P, Picchianti M, Balducci E, Biancucci M, Brock A, Berti F, Bottomley MJ, Nissum M, Costantino P, Rappuoli R, Spraggon G. Malito E, et al. Among authors: spraggon g. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5229-34. doi: 10.1073/pnas.1201964109. Epub 2012 Mar 19. Proc Natl Acad Sci U S A. 2012. PMID: 22431623 Free PMC article.
Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus.
Schluepen C, Malito E, Marongiu A, Schirle M, McWhinnie E, Lo Surdo P, Biancucci M, Falugi F, Nardi-Dei V, Marchi S, Fontana MR, Lombardi B, De Falco MG, Rinaudo CD, Spraggon G, Nissum M, Bagnoli F, Grandi G, Bottomley MJ, Liberatori S. Schluepen C, et al. Among authors: spraggon g. Biochem J. 2013 Nov 1;455(3):273-84. doi: 10.1042/BJ20130540. Biochem J. 2013. PMID: 23895222
FdeC, a novel broadly conserved Escherichia coli adhesin eliciting protection against urinary tract infections.
Nesta B, Spraggon G, Alteri C, Moriel DG, Rosini R, Veggi D, Smith S, Bertoldi I, Pastorello I, Ferlenghi I, Fontana MR, Frankel G, Mobley HL, Rappuoli R, Pizza M, Serino L, Soriani M. Nesta B, et al. Among authors: spraggon g. mBio. 2012 Apr 10;3(2):e00010-12. doi: 10.1128/mBio.00010-12. Print 2012. mBio. 2012. PMID: 22496310 Free PMC article.
Crystal structure of a two-subunit TrkA octameric gating ring assembly.
Deller MC, Johnson HA, Miller MD, Spraggon G, Elsliger MA, Wilson IA, Lesley SA. Deller MC, et al. Among authors: spraggon g. PLoS One. 2015 Mar 31;10(3):e0122512. doi: 10.1371/journal.pone.0122512. eCollection 2015. PLoS One. 2015. PMID: 25826626 Free PMC article.
Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
Cellitti SE, Shaffer J, Jones DH, Mukherjee T, Gurumurthy M, Bursulaya B, Boshoff HI, Choi I, Nayyar A, Lee YS, Cherian J, Niyomrattanakit P, Dick T, Manjunatha UH, Barry CE 3rd, Spraggon G, Geierstanger BH. Cellitti SE, et al. Among authors: spraggon g. Structure. 2012 Jan 11;20(1):101-12. doi: 10.1016/j.str.2011.11.001. Structure. 2012. PMID: 22244759 Free PMC article.
Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design.
Tully DC, Vidal A, Chatterjee AK, Williams JA, Roberts MJ, Petrassi HM, Spraggon G, Bursulaya B, Pacoma R, Shipway A, Schumacher AM, Danahay H, Harris JL. Tully DC, et al. Among authors: spraggon g. Bioorg Med Chem Lett. 2008 Nov 15;18(22):5895-9. doi: 10.1016/j.bmcl.2008.08.029. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18752942
125 results