Liu Z - Search Results

1

Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis.

Rathkey JK, Zhao J, Liu Z, Chen Y, Yang J, Kondolf HC, Benson BL, Chirieleison SM, Huang AY, Dubyak GR, Xiao TS, Li X, Abbott DW. Rathkey JK, et al. Among authors: liu z. Sci Immunol. 2018 Aug 24;3(26):eaat2738. doi: 10.1126/sciimmunol.aat2738. Sci Immunol. 2018. PMID: 30143556 Free PMC article.

2

STRUCTURAL BIOLOGY. Assembling the wheel of death.

Liu Z, Xiao TS. Liu Z, et al. Science. 2015 Oct 23;350(6259):376-7. doi: 10.1126/science.aad3981. Science. 2015. PMID: 26494742 Free PMC article. No abstract available.

3

Post-translational regulation of inflammasomes.

Yang J, Liu Z, Xiao TS. Yang J, et al. Among authors: liu z. Cell Mol Immunol. 2017 Jan;14(1):65-79. doi: 10.1038/cmi.2016.29. Epub 2016 Jun 27. Cell Mol Immunol. 2017. PMID: 27345727 Free PMC article. Review.

4

The G-quadruplex (G4) resolvase DHX36 efficiently and specifically disrupts DNA G4s via a translocation-based helicase mechanism.

Yangyuoru PM, Bradburn DA, Liu Z, Xiao TS, Russell R. Yangyuoru PM, et al. Among authors: liu z. J Biol Chem. 2018 Feb 9;293(6):1924-1932. doi: 10.1074/jbc.M117.815076. Epub 2017 Dec 21. J Biol Chem. 2018. PMID: 29269411 Free PMC article.

5

Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.

Liu Z, Wang C, Rathkey JK, Yang J, Dubyak GR, Abbott DW, Xiao TS. Liu Z, et al. Structure. 2018 May 1;26(5):778-784.e3. doi: 10.1016/j.str.2018.03.002. Epub 2018 Mar 22. Structure. 2018. PMID: 29576317 Free PMC article.

6

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.

Yang J, Liu Z, Wang C, Yang R, Rathkey JK, Pinkard OW, Shi W, Chen Y, Dubyak GR, Abbott DW, Xiao TS. Yang J, et al. Among authors: liu z. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6792-6797. doi: 10.1073/pnas.1800562115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891674 Free PMC article.

7

Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.

Liu Z, Wang C, Yang J, Zhou B, Yang R, Ramachandran R, Abbott DW, Xiao TS. Liu Z, et al. Immunity. 2019 Jul 16;51(1):43-49.e4. doi: 10.1016/j.immuni.2019.04.017. Epub 2019 May 13. Immunity. 2019. PMID: 31097341 Free PMC article.

8

Function of Auxiliary Domains of the DEAH/RHA Helicase DHX36 in RNA Remodeling.

Srinivasan S, Liu Z, Chuenchor W, Xiao TS, Jankowsky E. Srinivasan S, et al. Among authors: liu z. J Mol Biol. 2020 Mar 27;432(7):2217-2231. doi: 10.1016/j.jmb.2020.02.005. Epub 2020 Feb 19. J Mol Biol. 2020. PMID: 32087197 Free PMC article.

9

Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.

Liu Z, Wang C, Yang J, Chen Y, Zhou B, Abbott DW, Xiao TS. Liu Z, et al. Immunity. 2020 Jul 14;53(1):106-114.e5. doi: 10.1016/j.immuni.2020.06.007. Epub 2020 Jun 17. Immunity. 2020. PMID: 32553275 Free PMC article.

10

Partners with a killer: Metabolic signaling promotes inflammatory cell death.

Liu Z, Xiao TS. Liu Z, et al. Cell. 2021 Aug 19;184(17):4374-4376. doi: 10.1016/j.cell.2021.07.036. Cell. 2021. PMID: 34416144 Free PMC article.

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