Luthra P - Search Results

1

Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.

Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Luthra P, et al. Antiviral Res. 2018 Oct;158:288-302. doi: 10.1016/j.antiviral.2018.08.012. Epub 2018 Aug 23. Antiviral Res. 2018. PMID: 30144461 Free PMC article.

2

A high throughput screen identifies benzoquinoline compounds as inhibitors of Ebola virus replication.

Luthra P, Liang J, Pietzsch CA, Khadka S, Edwards MR, Wei S, De S, Posner B, Bukreyev A, Ready JM, Basler CF. Luthra P, et al. Antiviral Res. 2018 Feb;150:193-201. doi: 10.1016/j.antiviral.2017.12.019. Epub 2017 Dec 30. Antiviral Res. 2018. PMID: 29294299

3

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.

Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger LS, LaCount DJ, Davey RA, Amarasinghe GK, Basler CF, Krogan NJ. Batra J, et al. Among authors: luthra p. Cell. 2018 Dec 13;175(7):1917-1930.e13. doi: 10.1016/j.cell.2018.08.044. Cell. 2018. PMID: 30550789 Free PMC article.

4

Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways.

Williams CG, Gibbons JS, Keiffer TR, Luthra P, Edwards MR, Basler CF. Williams CG, et al. Among authors: luthra p. J Virol. 2020 Jun 16;94(13):e00191-20. doi: 10.1128/JVI.00191-20. Print 2020 Jun 16. J Virol. 2020. PMID: 32295912 Free PMC article.

5

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion.

Luthra P, Aguirre S, Yen BC, Pietzsch CA, Sanchez-Aparicio MT, Tigabu B, Morlock LK, García-Sastre A, Leung DW, Williams NS, Fernandez-Sesma A, Bukreyev A, Basler CF. Luthra P, et al. mBio. 2017 Apr 4;8(2):e00368-17. doi: 10.1128/mBio.00368-17. mBio. 2017. PMID: 28377530 Free PMC article.

6

Assays to Measure Suppression of Type I Interferon Responses by Filovirus VP35 Proteins.

Luthra P, Basler CF. Luthra P, et al. Methods Mol Biol. 2017;1628:133-142. doi: 10.1007/978-1-4939-7116-9_10. Methods Mol Biol. 2017. PMID: 28573616

7

The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.

Bharaj P, Atkins C, Luthra P, Giraldo MI, Dawes BE, Miorin L, Johnson JR, Krogan NJ, Basler CF, Freiberg AN, Rajsbaum R. Bharaj P, et al. Among authors: luthra p. J Virol. 2017 Aug 24;91(18):e00833-17. doi: 10.1128/JVI.00833-17. Print 2017 Sep 15. J Virol. 2017. PMID: 28679761 Free PMC article.

8

The Antiviral Drug Arbidol Inhibits Zika Virus.

Fink SL, Vojtech L, Wagoner J, Slivinski NSJ, Jackson KJ, Wang R, Khadka S, Luthra P, Basler CF, Polyak SJ. Fink SL, et al. Among authors: luthra p. Sci Rep. 2018 Jun 12;8(1):8989. doi: 10.1038/s41598-018-27224-4. Sci Rep. 2018. PMID: 29895962 Free PMC article.

9

Conservation of Structure and Immune Antagonist Functions of Filoviral VP35 Homologs Present in Microbat Genomes.

Edwards MR, Liu H, Shabman RS, Ginell GM, Luthra P, Ramanan P, Keefe LJ, Köllner B, Amarasinghe GK, Taylor DJ, Leung DW, Basler CF. Edwards MR, et al. Among authors: luthra p. Cell Rep. 2018 Jul 24;24(4):861-872.e6. doi: 10.1016/j.celrep.2018.06.045. Cell Rep. 2018. PMID: 30044983 Free PMC article.

10

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge.

Woolsey C, Menicucci AR, Cross RW, Luthra P, Agans KN, Borisevich V, Geisbert JB, Mire CE, Fenton KA, Jankeel A, Anand S, Ebihara H, Geisbert TW, Messaoudi I, Basler CF. Woolsey C, et al. Among authors: luthra p. Cell Rep. 2019 Sep 17;28(12):3032-3046.e6. doi: 10.1016/j.celrep.2019.08.047. Cell Rep. 2019. PMID: 31533029 Free PMC article.

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