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Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity.
Flamar AL, Klose CSN, Moeller JB, Mahlakõiv T, Bessman NJ, Zhang W, Moriyama S, Stokic-Trtica V, Rankin LC, Putzel GG, Rodewald HR, He Z, Chen L, Lira SA, Karsenty G, Artis D. Flamar AL, et al. Among authors: chen l. Immunity. 2020 Apr 14;52(4):606-619.e6. doi: 10.1016/j.immuni.2020.02.009. Epub 2020 Mar 10. Immunity. 2020. PMID: 32160524 Free PMC article.
IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.
Chen L, He Z, Slinger E, Bongers G, Lapenda TLS, Pacer ME, Jiao J, Beltrao MF, Soto AJ, Harpaz N, Gordon RE, Ochando JC, Oukka M, Iuga AC, Chensue SW, Blander JM, Furtado GC, Lira SA. Chen L, et al. Mucosal Immunol. 2015 Mar;8(2):390-402. doi: 10.1038/mi.2014.77. Epub 2014 Aug 27. Mucosal Immunol. 2015. PMID: 25160819 Free PMC article.
Diet Modifies Colonic Microbiota and CD4+ T-Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-Cell Expression of Interleukin 23.
Chen L, He Z, Iuga AC, Martins Filho SN, Faith JJ, Clemente JC, Deshpande M, Jayaprakash A, Colombel JF, Lafaille JJ, Sachidanandam R, Furtado GC, Lira SA. Chen L, et al. Gastroenterology. 2018 Oct;155(4):1177-1191.e16. doi: 10.1053/j.gastro.2018.06.034. Epub 2018 Jun 15. Gastroenterology. 2018. PMID: 29909020 Free PMC article.
Interleukin 22 disrupts pancreatic function in newborn mice expressing IL-23.
Chen L, Strohmeier V, He Z, Deshpande M, Catalan-Dibene J, Durum SK, Moran TM, Kraus T, Xiong H, Faith JJ, Sodhi CP, Hackam DJ, Lira SA, Furtado GC. Chen L, et al. Nat Commun. 2019 Oct 4;10(1):4517. doi: 10.1038/s41467-019-12540-8. Nat Commun. 2019. PMID: 31586069 Free PMC article.
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