Chen J - Search Results

1

A Pharmacokinetic/Pharmacodynamic Model to Predict Effective HIV Prophylaxis Dosing Strategies for People Who Inject Drugs.

Garrett KL, Chen J, Maas BM, Cottrell ML, Prince HA, Sykes C, Schauer AP, White N, Dumond JB. Garrett KL, et al. Among authors: chen j. J Pharmacol Exp Ther. 2018 Nov;367(2):245-251. doi: 10.1124/jpet.118.251009. Epub 2018 Aug 27. J Pharmacol Exp Ther. 2018. PMID: 30150483 Free PMC article.

2

Differential extracellular, but similar intracellular, disposition of two tenofovir formulations in the male genital tract.

Dumond JB, Greene SA, Prince HMA, Chen J, Maas BM, Sykes C, Schauer AP, Blake KH, Nelson JAE, Gay CL, Kashuba ADM, Cohen MS. Dumond JB, et al. Among authors: chen j. Antivir Ther. 2019;24(1):45-50. doi: 10.3851/IMP3277. Antivir Ther. 2019. PMID: 30375984 Free PMC article.

3

Population Modeling Highlights Drug Disposition Differences Between Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in the Blood and Semen.

Greene SA, Chen J, Prince HMA, Sykes C, Schauer AP, Blake K, Nelson JAE, Gay CL, Cohen MS, Dumond JB. Greene SA, et al. Among authors: chen j. Clin Pharmacol Ther. 2019 Oct;106(4):821-830. doi: 10.1002/cpt.1464. Epub 2019 May 31. Clin Pharmacol Ther. 2019. PMID: 31002391 Free PMC article.

4

Pharmacogenetic Analysis of the Model-Based Pharmacokinetics of Five Anti-HIV Drugs: How Does This Influence the Effect of Aging?

Chen J, Akhtari FS, Wagner MJ, Suzuki O, Wiltshire T, Motsinger-Reif AA, Dumond JB. Chen J, et al. Clin Transl Sci. 2018 Mar;11(2):226-236. doi: 10.1111/cts.12525. Epub 2017 Dec 3. Clin Transl Sci. 2018. PMID: 29205871 Free PMC article. Clinical Trial.

5

Model-Based Analysis of Unbound Lopinavir Pharmacokinetics in HIV-Infected Pregnant Women Supports Standard Dosing in the Third Trimester.

Chen J, Malone S, Prince HM, Patterson KB, Dumond JB. Chen J, et al. CPT Pharmacometrics Syst Pharmacol. 2016 Mar;5(3):147-57. doi: 10.1002/psp4.12065. Epub 2016 Mar 22. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27069778 Free PMC article.

6

Population Pharmacokinetics Modeling of Unbound Efavirenz, Atazanavir, and Ritonavir in HIV-Infected Subjects With Aging Biomarkers.

Dumond JB, Chen J, Cottrell M, Trezza CR, Prince H, Sykes C, Torrice C, White N, Malone S, Wang R, Patterson KB, Sharpless NE, Forrest A. Dumond JB, et al. Among authors: chen j. CPT Pharmacometrics Syst Pharmacol. 2017 Feb;6(2):128-135. doi: 10.1002/psp4.12151. Epub 2016 Dec 29. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28032946 Free PMC article. Clinical Trial.

7

The effect of age on CD4+ T-cell recovery in HIV-suppressed adult participants: a sub-study from AIDS Clinical Trial Group (ACTG) A5321 and the Bone Loss and Immune Reconstitution (BLIR) study.

Chen J, Titanji K, Sheth AN, Gandhi R, McMahon D, Ofotokun I, Weitzmann MN, De Paris K, Dumond JB. Chen J, et al. Immun Ageing. 2022 Jan 3;19(1):4. doi: 10.1186/s12979-021-00260-x. Immun Ageing. 2022. PMID: 34980186 Free PMC article.

8

Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis.

Maas BM, Lommerse J, Plock N, Railkar RA, Cheung SYA, Caro L, Chen J, Liu W, Zhang Y, Huang Q, Gao W, Qin L, Meng J, Witjes H, Schindler E, Guiastrennec B, Bellanti F, Spellman DS, Roadcap B, Kalinova M, Fok-Seang J, Catchpole AP, Espeseth AS, Stoch SA, Lai E, Vora KA, Aliprantis AO, Sachs JR. Maas BM, et al. Among authors: chen j. EBioMedicine. 2021 Nov;73:103651. doi: 10.1016/j.ebiom.2021.103651. Epub 2021 Nov 11. EBioMedicine. 2021. PMID: 34775220 Free PMC article.

9

Nanodrugs Targeting Key Factors of Ferroptosis Regulation for Enhanced Treatment of Osteoarthritis.

Wang D, Pan Y, Chen W, He D, Qi W, Chen J, Yuan W, Yang Y, Chen D, Wang P, Jin H. Wang D, et al. Among authors: chen j. Adv Sci (Weinh). 2025 Jan 22:e2412817. doi: 10.1002/advs.202412817. Online ahead of print. Adv Sci (Weinh). 2025. PMID: 39840543

10

Drug-Drug Interaction Between Rifampicin and Albuvirtide: A Phase 1, Randomized, Open-Label Study.

Zhang L, Chen J, Lin XY, Lu Y, Wu Y, Wu YJ, Meng XM. Zhang L, et al. Among authors: chen j. J Clin Pharmacol. 2025 Jan 22. doi: 10.1002/jcph.6191. Online ahead of print. J Clin Pharmacol. 2025. PMID: 39840531

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