Howitz WJ - Search Results

1

Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture.

Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Manna S, et al. Among authors: howitz wj. ACS Cent Sci. 2018 Aug 22;4(8):982-995. doi: 10.1021/acscentsci.8b00218. Epub 2018 Jul 2. ACS Cent Sci. 2018. PMID: 30159395 Free PMC article.

2

Correction to "Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture".

Manna S, Howitz WJ, Oldenhuis NJ, Eldredge AC, Shen J, Nihesh FN, Lodoen MB, Guan Z, Esser-Kahn AP. Manna S, et al. Among authors: howitz wj. ACS Cent Sci. 2018 Nov 28;4(11):1593. doi: 10.1021/acscentsci.8b00752. Epub 2018 Oct 31. ACS Cent Sci. 2018. PMID: 30555913 Free PMC article.

3

Receptor-Ligand Kinetics Influence the Mechanism of Action of Covalently Linked TLR Ligands.

Kimani FW, Ajit J, Galluppi A, Manna S, Howitz WJ, Tang S, Esser-Kahn AP. Kimani FW, et al. Among authors: howitz wj. ACS Chem Biol. 2021 Feb 19;16(2):380-388. doi: 10.1021/acschembio.0c00924. Epub 2021 Feb 1. ACS Chem Biol. 2021. PMID: 33523635 Free PMC article.

4

Macrocyclic Peptides Derived from Familial Alzheimer's Disease Mutants Show Charge-Dependent Oligomeric Assembly and Toxicity.

Howitz WJ, Guaglianone G, McKnelly KJ, Haduong K, Ashby SN, Laayouni M, Nowick JS. Howitz WJ, et al. ACS Chem Neurosci. 2022 Mar 16;13(6):714-720. doi: 10.1021/acschemneuro.1c00833. Epub 2022 Feb 22. ACS Chem Neurosci. 2022. PMID: 35191689 Free PMC article.

5

Effects of N-Terminal Residues on the Assembly of Constrained β-Hairpin Peptides Derived from Aβ.

Samdin TD, Wierzbicki M, Kreutzer AG, Howitz WJ, Valenzuela M, Smith A, Sahrai V, Truex NL, Klun M, Nowick JS. Samdin TD, et al. Among authors: howitz wj. J Am Chem Soc. 2020 Jul 1;142(26):11593-11601. doi: 10.1021/jacs.0c05186. Epub 2020 Jun 22. J Am Chem Soc. 2020. PMID: 32501687 Free PMC article.

6

Effects of Familial Alzheimer's Disease Mutations on the Assembly of a β-Hairpin Peptide Derived from Aβ_16-36.

McKnelly KJ, Kreutzer AG, Howitz WJ, Haduong K, Yoo S, Hart C, Nowick JS. McKnelly KJ, et al. Among authors: howitz wj. Biochemistry. 2022 Mar 15;61(6):446-454. doi: 10.1021/acs.biochem.1c00664. Epub 2022 Feb 25. Biochemistry. 2022. PMID: 35213141 Free PMC article.

7

Expression of N-Terminal Cysteine Aβ₄₂ and Conjugation to Generate Fluorescent and Biotinylated Aβ₄₂.

Zhang S, Guaglianone G, Morris MA, Yoo S, Howitz WJ, Xing L, Zheng JG, Jusuf H, Huizar G, Lin J, Kreutzer AG, Nowick JS. Zhang S, et al. Among authors: howitz wj. Biochemistry. 2021 Apr 20;60(15):1191-1200. doi: 10.1021/acs.biochem.1c00105. Epub 2021 Apr 1. Biochemistry. 2021. PMID: 33793198 Free PMC article.

8

Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin_19-36.

Howitz WJ, Wierzbicki M, Cabanela RW, Saliba C, Motavalli A, Tran N, Nowick JS. Howitz WJ, et al. J Am Chem Soc. 2020 Sep 16;142(37):15870-15875. doi: 10.1021/jacs.0c06143. Epub 2020 Sep 3. J Am Chem Soc. 2020. PMID: 32816461 Free PMC article.

9

Correction to "Interpenetrating Cubes in the X-ray Crystallographic Structure of a Peptide Derived from Medin_19-36".

Howitz WJ, Wierzbicki M, Cabanela RW, Saliba C, Motavalli A, Tran N, Nowick JS. Howitz WJ, et al. J Am Chem Soc. 2020 Nov 4;142(44):18998. doi: 10.1021/jacs.0c10779. Epub 2020 Oct 21. J Am Chem Soc. 2020. PMID: 33086010 No abstract available.

10

Correction to "Expression of N-Terminal Cysteine Aβ₄₂ and Conjugation to Generate Fluorescent and Biotinylated Aβ₄₂".

Zhang S, Guaglianone G, Morris MA, Yoo S, Howitz WJ, Xing L, Zheng JG, Jusuf H, Huizar G, Lin J, Kreutzer AG, Nowick JS. Zhang S, et al. Among authors: howitz wj. Biochemistry. 2021 Jul 20;60(28):2272-2273. doi: 10.1021/acs.biochem.1c00424. Epub 2021 Jul 2. Biochemistry. 2021. PMID: 34213906 No abstract available.

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