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Ficolin-1 is a promising therapeutic target for autoimmune diseases.
Katayama M, Ota K, Nagi-Miura N, Ohno N, Yabuta N, Nojima H, Kumanogoh A, Hirano T. Katayama M, et al. Among authors: hirano t. Int Immunol. 2019 Feb 6;31(1):23-32. doi: 10.1093/intimm/dxy056. Int Immunol. 2019. PMID: 30169661 Free PMC article.
Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications.
Yoshida Y, Ogata A, Kang S, Ebina K, Shi K, Nojima S, Kimura T, Ito D, Morimoto K, Nishide M, Hosokawa T, Hirano T, Shima Y, Narazaki M, Tsuboi H, Saeki Y, Tomita T, Tanaka T, Kumanogoh A. Yoshida Y, et al. Among authors: hirano t. Arthritis Rheumatol. 2015 Jun;67(6):1481-90. doi: 10.1002/art.39086. Arthritis Rheumatol. 2015. PMID: 25707877 Free PMC article.
LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation.
Morimoto K, Baba Y, Shinohara H, Kang S, Nojima S, Kimura T, Ito D, Yoshida Y, Maeda Y, Sarashina-Kida H, Nishide M, Hosokawa T, Kato Y, Hayama Y, Kinehara Y, Okuno T, Takamatsu H, Hirano T, Shima Y, Narazaki M, Kurosaki T, Toyofuku T, Kumanogoh A. Morimoto K, et al. Among authors: hirano t. Sci Rep. 2016 May 11;6:25738. doi: 10.1038/srep25738. Sci Rep. 2016. PMID: 27166870 Free PMC article.
Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.
Nishide M, Nojima S, Ito D, Takamatsu H, Koyama S, Kang S, Kimura T, Morimoto K, Hosokawa T, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Nakanishi Y, Tsuda T, Park JH, Hirano T, Shima Y, Narazaki M, Morii E, Kumanogoh A. Nishide M, et al. Among authors: hirano t. Ann Rheum Dis. 2017 Aug;76(8):1440-1448. doi: 10.1136/annrheumdis-2016-210706. Epub 2017 Apr 17. Ann Rheum Dis. 2017. PMID: 28416516 Free PMC article.
Drug retention and discontinuation reasons between seven biologics in patients with rheumatoid arthritis -The ANSWER cohort study.
Ebina K, Hashimoto M, Yamamoto W, Ohnishi A, Kabata D, Hirano T, Hara R, Katayama M, Yoshida S, Nagai K, Son Y, Amuro H, Akashi K, Fujimura T, Hirao M, Yamamoto K, Shintani A, Kumanogoh A, Yoshikawa H. Ebina K, et al. Among authors: hirano t. PLoS One. 2018 Mar 15;13(3):e0194130. doi: 10.1371/journal.pone.0194130. eCollection 2018. PLoS One. 2018. PMID: 29543846 Free PMC article.
4,280 results