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Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death.
Keatinge M, Bui H, Menke A, Chen YC, Sokol AM, Bai Q, Ellett F, Da Costa M, Burke D, Gegg M, Trollope L, Payne T, McTighe A, Mortiboys H, de Jager S, Nuthall H, Kuo MS, Fleming A, Schapira AH, Renshaw SA, Highley JR, Chacinska A, Panula P, Burton EA, O'Neill MJ, Bandmann O. Keatinge M, et al. Among authors: ellett f. Hum Mol Genet. 2015 Dec 1;24(23):6640-52. doi: 10.1093/hmg/ddv369. Epub 2015 Sep 16. Hum Mol Genet. 2015. PMID: 26376862 Free PMC article.
Semaphorin 3F signaling actively retains neutrophils at sites of inflammation.
Plant T, Eamsamarng S, Sanchez-Garcia MA, Reyes L, Renshaw SA, Coelho P, Mirchandani AS, Morgan JM, Ellett FE, Morrison T, Humphries D, Watts ER, Murphy F, Raffo-Iraolagoitia XL, Zhang A, Cash JL, Loynes C, Elks PM, Van Eeden F, Carlin LM, Furley AJ, Whyte MK, Walmsley SR. Plant T, et al. Among authors: ellett fe. J Clin Invest. 2020 Jun 1;130(6):3221-3237. doi: 10.1172/JCI130834. J Clin Invest. 2020. PMID: 32191647 Free PMC article.
Impact of toll-like receptor 4 stimulation on human neonatal neutrophil spontaneous migration, transcriptomics, and cytokine production.
Raymond SL, Hawkins RB, Murphy TJ, Rincon JC, Stortz JA, López MC, Ungaro R, Ellett F, Baker HV, Wynn JL, Moldawer LL, Irimia D, Larson SD. Raymond SL, et al. Among authors: ellett f. J Mol Med (Berl). 2018 Jul;96(7):673-684. doi: 10.1007/s00109-018-1646-5. Epub 2018 May 28. J Mol Med (Berl). 2018. PMID: 29808244 Free PMC article.
58 results