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Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse.
Bollyky PL, Evanko SP, Wu RP, Potter-Perigo S, Long SA, Kinsella B, Reijonen H, Guebtner K, Teng B, Chan CK, Braun KR, Gebe JA, Nepom GT, Wight TN. Bollyky PL, et al. Among authors: wight tn. Cell Mol Immunol. 2010 May;7(3):211-20. doi: 10.1038/cmi.2010.9. Epub 2010 Mar 15. Cell Mol Immunol. 2010. PMID: 20228832 Free PMC article.
ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors.
Bollyky PL, Wu RP, Falk BA, Lord JD, Long SA, Preisinger A, Teng B, Holt GE, Standifer NE, Braun KR, Xie CF, Samuels PL, Vernon RB, Gebe JA, Wight TN, Nepom GT. Bollyky PL, et al. Among authors: wight tn. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7938-43. doi: 10.1073/pnas.1017360108. Epub 2011 Apr 25. Proc Natl Acad Sci U S A. 2011. PMID: 21518860 Free PMC article.
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1.
Kanter JE, Kramer F, Barnhart S, Averill MM, Vivekanandan-Giri A, Vickery T, Li LO, Becker L, Yuan W, Chait A, Braun KR, Potter-Perigo S, Sanda S, Wight TN, Pennathur S, Serhan CN, Heinecke JW, Coleman RA, Bornfeldt KE. Kanter JE, et al. Among authors: wight tn. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):E715-24. doi: 10.1073/pnas.1111600109. Epub 2012 Jan 17. Proc Natl Acad Sci U S A. 2012. PMID: 22308341 Free PMC article.
Cleavage of hyaluronan is impaired in aged dermal wounds.
Reed MJ, Damodarasamy M, Chan CK, Johnson MN, Wight TN, Vernon RB. Reed MJ, et al. Among authors: wight tn. Matrix Biol. 2013 Jan;32(1):45-51. doi: 10.1016/j.matbio.2012.09.004. Epub 2012 Sep 27. Matrix Biol. 2013. PMID: 23022999 Free PMC article.
340 results