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( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.
Liu Y, Ji L, Eno M, Kudalkar S, Li AL, Schimpgen M, Benchama O, Morales P, Xu S, Hurst D, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis DP, Zhou H, Honrao C, Mackie K, Reggio P, Hohmann AG, Marnett LJ, Makriyannis A, Nikas SP. Liu Y, et al. Among authors: wood jt. J Med Chem. 2018 Oct 11;61(19):8639-8657. doi: 10.1021/acs.jmedchem.8b00611. Epub 2018 Sep 21. J Med Chem. 2018. PMID: 30196704
Controlled-deactivation cannabinergic ligands.
Sharma R, Nikas SP, Paronis CA, Wood JT, Halikhedkar A, Guo JJ, Thakur GA, Kulkarni S, Benchama O, Raghav JG, Gifford RS, Järbe TU, Bergman J, Makriyannis A. Sharma R, et al. Among authors: wood jt. J Med Chem. 2013 Dec 27;56(24):10142-57. doi: 10.1021/jm4016075. Epub 2013 Dec 10. J Med Chem. 2013. PMID: 24286207 Free PMC article.
C-ring cannabinoid lactones: a novel cannabinergic chemotype.
Sharma R, Nikas SP, Guo JJ, Mallipeddi S, Wood JT, Makriyannis A. Sharma R, et al. Among authors: wood jt. ACS Med Chem Lett. 2014 Jan 14;5(4):400-4. doi: 10.1021/ml4005304. eCollection 2014 Apr 10. ACS Med Chem Lett. 2014. PMID: 24900848 Free PMC article.
Oximes short-acting CB1 receptor agonists.
Malamas MS, Raghav JG, Ma X, Honrao C, Wood JT, Benchama O, Zhou H, Mallipeddi S, Makriyannis A. Malamas MS, et al. Among authors: wood jt. Bioorg Med Chem. 2018 Oct 1;26(18):4963-4970. doi: 10.1016/j.bmc.2018.08.003. Epub 2018 Aug 2. Bioorg Med Chem. 2018. PMID: 30122284
Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists.
Papanastasiou IP, Georgiadis MO, Iliopoulos-Tsoutsouvas C, Paronis CA, Brust CA, Tran NK, Ji L, Ma X, Wood JT, Zvonok N, Tong F, Bohn LM, Nikas SP, Makriyannis A. Papanastasiou IP, et al. Among authors: wood jt. Eur J Med Chem. 2022 Feb 15;230:114027. doi: 10.1016/j.ejmech.2021.114027. Epub 2021 Dec 27. Eur J Med Chem. 2022. PMID: 35051750
Conformationally constrained analogues of 2-arachidonoylglycerol.
Vadivel SK, Vardarajan S, Duclos RI Jr, Wood JT, Guo J, Makriyannis A. Vadivel SK, et al. Among authors: wood jt. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5959-63. doi: 10.1016/j.bmcl.2007.07.064. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17826996 Free PMC article.
A comparison of novel, selective fatty acid amide hydrolase (FAAH), monoacyglycerol lipase (MAGL) or dual FAAH/MAGL inhibitors to suppress acute and anticipatory nausea in rat models.
Parker LA, Limebeer CL, Rock EM, Sticht MA, Ward J, Turvey G, Benchama O, Rajarshi G, Wood JT, Alapafuja SO, Makriyannis A. Parker LA, et al. Among authors: wood jt. Psychopharmacology (Berl). 2016 Jun;233(12):2265-75. doi: 10.1007/s00213-016-4277-y. Epub 2016 Apr 6. Psychopharmacology (Berl). 2016. PMID: 27048155 Free PMC article.
69 results