Morser J - Search Results

1

Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis.

Islam I, Yuan S, West CW, Adler M, Bothe U, Bryant J, Chang Z, Chu K, Emayan K, Gualtieri G, Ho E, Light D, Mallari C, Morser J, Phillips G, Schaefer C, Sukovich D, Whitlow M, Chen D, Buckman BO. Islam I, et al. Among authors: morser j. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3372-3375. doi: 10.1016/j.bmcl.2018.09.001. Epub 2018 Sep 5. Bioorg Med Chem Lett. 2018. PMID: 30201291

2

3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa).

Islam I, Bryant J, May K, Mohan R, Yuan S, Kent L, Morser J, Zhao L, Vergona R, White K, Adler M, Whitlow M, Buckman BO. Islam I, et al. Among authors: morser j. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1349-54. doi: 10.1016/j.bmcl.2006.11.078. Epub 2006 Dec 3. Bioorg Med Chem Lett. 2007. PMID: 17189688

3

A novel inhibitor of activated thrombin activatable fibrinolysis inhibitor (TAFIa) - part II: enhancement of both exogenous and endogenous fibrinolysis in animal models of thrombosis.

Wang YX, da Cunha V, Vincelette J, Zhao L, Nagashima M, Kawai K, Yuan S, Emayan K, Islam I, Hosoya J, Sullivan ME, Dole WP, Morser J, Buckman BO, Vergona R. Wang YX, et al. Among authors: morser j. Thromb Haemost. 2007 Jan;97(1):54-61. Thromb Haemost. 2007. PMID: 17200771

4

Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.

Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ. Ye B, et al. Among authors: morser j. J Med Chem. 2007 Jun 28;50(13):2967-80. doi: 10.1021/jm070125f. Epub 2007 May 31. J Med Chem. 2007. PMID: 17536795

5

Structures of potent selective peptide mimetics bound to carboxypeptidase B.

Adler M, Buckman B, Bryant J, Chang Z, Chu K, Emayan K, Hrvatin P, Islam I, Morser J, Sukovich D, West C, Yuan S, Whitlow M. Adler M, et al. Among authors: morser j. Acta Crystallogr D Biol Crystallogr. 2008 Feb;64(Pt 2):149-57. doi: 10.1107/S0907444907057228. Epub 2008 Jan 16. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18219114

6

A novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor (TAFIa) - part I: pharmacological characterization.

Wang YX, Zhao L, Nagashima M, Vincelette J, Sukovich D, Li W, Subramanyam B, Yuan S, Emayan K, Islam I, Hrvatin P, Bryant J, Light DR, Vergona R, Morser J, Buckman BO. Wang YX, et al. Among authors: morser j. Thromb Haemost. 2007 Jan;97(1):45-53. Thromb Haemost. 2007. PMID: 17200770

7

A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models.

Wang YX, Vincelette J, da Cunha V, Martin-McNulty B, Mallari C, Fitch RM, Alexander S, Islam I, Buckman BO, Yuan S, Post JM, Subramanyam B, Vergona R, Sullivan ME, Dole WP, Morser J, Bryant J. Wang YX, et al. Among authors: morser j. Thromb Haemost. 2007 May;97(5):847-55. Thromb Haemost. 2007. PMID: 17479197

8

Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (I): in vitro effects on platelets.

Bryant J, Post JM, Alexander S, Wang YX, Kent L, Schirm S, Tseng JL, Subramanyam B, Buckman B, Islam I, Yuan S, Sullivan ME, Snider M, Morser J. Bryant J, et al. Among authors: morser j. Thromb Res. 2008;122(4):523-32. doi: 10.1016/j.thromres.2008.03.026. Epub 2008 May 20. Thromb Res. 2008. PMID: 18495218

9

Discovery and characterization of a potent and selective non-amidine inhibitor of human factor Xa.

Liang AM, Light DR, Kochanny M, Rumennik G, Trinh L, Lentz D, Post J, Morser J, Snider M. Liang AM, et al. Among authors: morser j. Biochem Pharmacol. 2003 May 1;65(9):1407-18. doi: 10.1016/s0006-2952(03)00084-4. Biochem Pharmacol. 2003. PMID: 12732352

10

Mutations in the substrate binding site of thrombin-activatable fibrinolysis inhibitor (TAFI) alter its substrate specificity.

Zhao L, Buckman B, Seto M, Morser J, Nagashima M. Zhao L, et al. Among authors: morser j. J Biol Chem. 2003 Aug 22;278(34):32359-66. doi: 10.1074/jbc.M300803200. Epub 2003 Jun 10. J Biol Chem. 2003. PMID: 12799375 Free article.

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