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Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.
Zhang C, Seo J, Murakami K, Salem ESB, Bernhard E, Borra VJ, Choi K, Yuan CL, Chan CC, Chen X, Huang T, Weirauch MT, Divanovic S, Qi NR, Thomas HE, Mercer CA, Siomi H, Nakamura T. Zhang C, et al. Among authors: weirauch mt. Nat Commun. 2018 Sep 10;9(1):3658. doi: 10.1038/s41467-018-05870-6. Nat Commun. 2018. PMID: 30201950 Free PMC article.
MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis.
Pan W, Zhu S, Dai D, Liu Z, Li D, Li B, Gagliani N, Zheng Y, Tang Y, Weirauch MT, Chen X, Zhu W, Wang Y, Chen B, Qian Y, Chen Y, Fang J, Herbst R, Richman L, Jallal B, Harley JB, Flavell RA, Yao Y, Shen N. Pan W, et al. Among authors: weirauch mt. Nat Commun. 2015 May 12;6:7096. doi: 10.1038/ncomms8096. Nat Commun. 2015. PMID: 25963922 Free article.
Transcription Factor Repertoire of Homeostatic Eosinophilopoiesis.
Bouffi C, Kartashov AV, Schollaert KL, Chen X, Bacon WC, Weirauch MT, Barski A, Fulkerson PC. Bouffi C, et al. Among authors: weirauch mt. J Immunol. 2015 Sep 15;195(6):2683-95. doi: 10.4049/jimmunol.1500510. Epub 2015 Aug 12. J Immunol. 2015. PMID: 26268651 Free PMC article.
Multiple layers of transcriptional regulation by PLZF in NKT-cell development.
Mao AP, Constantinides MG, Mathew R, Zuo Z, Chen X, Weirauch MT, Bendelac A. Mao AP, et al. Among authors: weirauch mt. Proc Natl Acad Sci U S A. 2016 Jul 5;113(27):7602-7. doi: 10.1073/pnas.1601504113. Epub 2016 Jun 20. Proc Natl Acad Sci U S A. 2016. PMID: 27325774 Free PMC article.
Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.
Fang J, Bolanos LC, Choi K, Liu X, Christie S, Akunuru S, Kumar R, Wang D, Chen X, Greis KD, Stoilov P, Filippi MD, Maciejewski JP, Garcia-Manero G, Weirauch MT, Salomonis N, Geiger H, Zheng Y, Starczynowski DT. Fang J, et al. Among authors: weirauch mt. Nat Immunol. 2017 Feb;18(2):236-245. doi: 10.1038/ni.3654. Epub 2016 Dec 26. Nat Immunol. 2017. PMID: 28024152 Free PMC article.
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity.
Harley JB, Chen X, Pujato M, Miller D, Maddox A, Forney C, Magnusen AF, Lynch A, Chetal K, Yukawa M, Barski A, Salomonis N, Kaufman KM, Kottyan LC, Weirauch MT. Harley JB, et al. Among authors: weirauch mt. Nat Genet. 2018 May;50(5):699-707. doi: 10.1038/s41588-018-0102-3. Epub 2018 Apr 16. Nat Genet. 2018. PMID: 29662164 Free PMC article.
AMP kinase promotes glioblastoma bioenergetics and tumour growth.
Chhipa RR, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, Chen X, Waclaw R, Chow LM, Khuchua Z, Kofron M, Weirauch MT, Kendler A, McPherson C, Ratner N, Nakano I, Dasgupta N, Komurov K, Dasgupta B. Chhipa RR, et al. Among authors: weirauch mt. Nat Cell Biol. 2018 Jul;20(7):823-835. doi: 10.1038/s41556-018-0126-z. Epub 2018 Jun 18. Nat Cell Biol. 2018. PMID: 29915361 Free PMC article.
192 results