Hancock JF - Search Results

1

Neratinib augments the lethality of [regorafenib + sildenafil].

Booth L, Roberts JL, Rais R, Cutler RE Jr, Diala I, Lalani AS, Hancock JF, Poklepovic A, Dent P. Booth L, et al. Among authors: hancock jf. J Cell Physiol. 2019 Apr;234(4):4874-4887. doi: 10.1002/jcp.27276. Epub 2018 Sep 10. J Cell Physiol. 2019. PMID: 30203445 Free PMC article.

2

AMPK and Endothelial Nitric Oxide Synthase Signaling Regulates K-Ras Plasma Membrane Interactions via Cyclic GMP-Dependent Protein Kinase 2.

Cho KJ, Casteel DE, Prakash P, Tan L, van der Hoeven D, Salim AA, Kim C, Capon RJ, Lacey E, Cunha SR, Gorfe AA, Hancock JF. Cho KJ, et al. Among authors: hancock jf. Mol Cell Biol. 2016 Nov 28;36(24):3086-3099. doi: 10.1128/MCB.00365-16. Print 2016 Dec 15. Mol Cell Biol. 2016. PMID: 27697864 Free PMC article.

3

Neratinib and entinostat combine to rapidly reduce the expression of K-RAS, N-RAS, Gα_q and Gα₁₁ and kill uveal melanoma cells.

Booth L, Roberts JL, Sander C, Lalani AS, Kirkwood JM, Hancock JF, Poklepovic A, Dent P. Booth L, et al. Among authors: hancock jf. Cancer Biol Ther. 2019;20(5):700-710. doi: 10.1080/15384047.2018.1551747. Epub 2018 Dec 20. Cancer Biol Ther. 2019. PMID: 30571927 Free PMC article.

4

Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells.

Dent P, Booth L, Roberts JL, Liu J, Poklepovic A, Lalani AS, Tuveson D, Martinez J, Hancock JF. Dent P, et al. Among authors: hancock jf. Oncogene. 2019 Jul;38(30):5890-5904. doi: 10.1038/s41388-019-0849-8. Epub 2019 Jun 28. Oncogene. 2019. PMID: 31253872 Free PMC article.

5

Signaling alterations caused by drugs and autophagy.

Dent P, Booth L, Poklepovic A, Hancock JF. Dent P, et al. Among authors: hancock jf. Cell Signal. 2019 Dec;64:109416. doi: 10.1016/j.cellsig.2019.109416. Epub 2019 Sep 11. Cell Signal. 2019. PMID: 31520735 Review.

6

Enhanced signaling via ERBB3/PI3K plays a compensatory survival role in pancreatic tumor cells exposed to [neratinib + valproate].

Dent P, Booth L, Poklepovic A, Hoff DV, Hancock JF. Dent P, et al. Among authors: hancock jf. Cell Signal. 2020 Apr;68:109525. doi: 10.1016/j.cellsig.2020.109525. Epub 2020 Jan 3. Cell Signal. 2020. PMID: 31911180 Free article.

7

Neratinib degrades MST4 via autophagy that reduces membrane stiffness and is essential for the inactivation of PI3K, ERK1/2, and YAP/TAZ signaling.

Dent P, Booth L, Poklepovic A, Martinez J, Hoff DV, Hancock JF. Dent P, et al. Among authors: hancock jf. J Cell Physiol. 2020 Nov;235(11):7889-7899. doi: 10.1002/jcp.29443. Epub 2020 Jan 8. J Cell Physiol. 2020. PMID: 31912905 Free PMC article.

8

(Curcumin+sildenafil) enhances the efficacy of 5FU and anti-PD1 therapies in vivo.

Dent P, Booth L, Roberts JL, Poklepovic A, Hancock JF. Dent P, et al. Among authors: hancock jf. J Cell Physiol. 2020 Oct;235(10):6862-6874. doi: 10.1002/jcp.29580. Epub 2020 Jan 27. J Cell Physiol. 2020. PMID: 31985048

9

Fingolimod Augments Monomethylfumarate Killing of GBM Cells.

Dent P, Booth L, Roberts JL, Poklepovic A, Hancock JF. Dent P, et al. Among authors: hancock jf. Front Oncol. 2020 Jan 28;10:22. doi: 10.3389/fonc.2020.00022. eCollection 2020. Front Oncol. 2020. PMID: 32047722 Free PMC article.

10

Corrigendum: Fingolimod Augments Monomethylfumarate Killing of GBM Cells.

Dent P, Booth L, Roberts JL, Poklepovic A, Hancock JF. Dent P, et al. Among authors: hancock jf. Front Oncol. 2020 Apr 30;10:684. doi: 10.3389/fonc.2020.00684. eCollection 2020. Front Oncol. 2020. PMID: 32426288 Free PMC article.

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