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A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding.
Chrudinová M, Žáková L, Marek A, Socha O, Buděšínský M, Hubálek M, Pícha J, Macháčková K, Jiráček J, Selicharová I. Chrudinová M, et al. Among authors: selicharova i. J Biol Chem. 2018 Oct 26;293(43):16818-16829. doi: 10.1074/jbc.RA118.004852. Epub 2018 Sep 13. J Biol Chem. 2018. PMID: 30213860 Free PMC article.
Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Viková J, Collinsová M, Kletvíková E, Buděšínský M, Kaplan V, Žáková L, Veverka V, Hexnerová R, Tarazona Aviñó RJ, Straková J, Selicharová I, Vaněk V, Wright DW, Watson CJ, Turkenburg JP, Brzozowski AM, Jiráček J. Viková J, et al. Among authors: selicharova i. Sci Rep. 2016 Jan 21;6:19431. doi: 10.1038/srep19431. Sci Rep. 2016. PMID: 26792393 Free PMC article.
29 results