Paulson HL - Search Results

1

Loss of the Spinocerebellar Ataxia type 3 disease protein ATXN3 alters transcription of multiple signal transduction pathways.

Zeng L, Zhang D, McLoughlin HS, Zalon AJ, Aravind L, Paulson HL. Zeng L, et al. Among authors: paulson hl. PLoS One. 2018 Sep 19;13(9):e0204438. doi: 10.1371/journal.pone.0204438. eCollection 2018. PLoS One. 2018. PMID: 30231063 Free PMC article.

2

Oligonucleotide therapy mitigates disease in spinocerebellar ataxia type 3 mice.

McLoughlin HS, Moore LR, Chopra R, Komlo R, McKenzie M, Blumenstein KG, Zhao H, Kordasiewicz HB, Shakkottai VG, Paulson HL. McLoughlin HS, et al. Among authors: paulson hl. Ann Neurol. 2018 Jul;84(1):64-77. doi: 10.1002/ana.25264. Epub 2018 Aug 6. Ann Neurol. 2018. PMID: 29908063 Free PMC article.

3

Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line.

Moore LR, Keller L, Bushart DD, Delatorre RG, Li D, McLoughlin HS, do Carmo Costa M, Shakkottai VG, Smith GD, Paulson HL. Moore LR, et al. Among authors: paulson hl. Stem Cell Res. 2019 Aug;39:101504. doi: 10.1016/j.scr.2019.101504. Epub 2019 Jul 16. Stem Cell Res. 2019. PMID: 31374463 Free PMC article.

4

Pathogenesis of SCA3 and implications for other polyglutamine diseases.

McLoughlin HS, Moore LR, Paulson HL. McLoughlin HS, et al. Among authors: paulson hl. Neurobiol Dis. 2020 Feb;134:104635. doi: 10.1016/j.nbd.2019.104635. Epub 2019 Oct 24. Neurobiol Dis. 2020. PMID: 31669734 Free PMC article. Review.

5

In Vivo Molecular Signatures of Cerebellar Pathology in Spinocerebellar Ataxia Type 3.

Costa MDC, Radzwion M, McLoughlin HS, Ashraf NS, Fischer S, Shakkottai VG, Maciel P, Paulson HL, Öz G. Costa MDC, et al. Among authors: paulson hl. Mov Disord. 2020 Oct;35(10):1774-1786. doi: 10.1002/mds.28140. Epub 2020 Jul 4. Mov Disord. 2020. PMID: 32621646 Free PMC article.

6

Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3.

Bushart DD, Zalon AJ, Zhang H, Morrison LM, Guan Y, Paulson HL, Shakkottai VG, McLoughlin HS. Bushart DD, et al. Among authors: paulson hl. Cerebellum. 2021 Feb;20(1):41-53. doi: 10.1007/s12311-020-01179-7. Cerebellum. 2021. PMID: 32789747 Free PMC article.

7

Impaired Oligodendrocyte Maturation Is an Early Feature in SCA3 Disease Pathogenesis.

Schuster KH, Zalon AJ, Zhang H, DiFranco DM, Stec NR, Haque Z, Blumenstein KG, Pierce AM, Guan Y, Paulson HL, McLoughlin HS. Schuster KH, et al. Among authors: paulson hl. J Neurosci. 2022 Feb 23;42(8):1604-1617. doi: 10.1523/JNEUROSCI.1954-20.2021. Epub 2022 Jan 18. J Neurosci. 2022. PMID: 35042771 Free PMC article.

8

Evaluation of Antisense Oligonucleotides Targeting ATXN3 in SCA3 Mouse Models.

Moore LR, Rajpal G, Dillingham IT, Qutob M, Blumenstein KG, Gattis D, Hung G, Kordasiewicz HB, Paulson HL, McLoughlin HS. Moore LR, et al. Among authors: paulson hl. Mol Ther Nucleic Acids. 2017 Jun 16;7:200-210. doi: 10.1016/j.omtn.2017.04.005. Epub 2017 Apr 12. Mol Ther Nucleic Acids. 2017. PMID: 28624196 Free PMC article.

9

The de-ubiquitinating enzyme ataxin-3 does not modulate disease progression in a knock-in mouse model of Huntington disease.

Zeng L, Tallaksen-Greene SJ, Wang B, Albin RL, Paulson HL. Zeng L, et al. Among authors: paulson hl. J Huntingtons Dis. 2013;2(2):201-15. doi: 10.3233/JHD-130058. J Huntingtons Dis. 2013. PMID: 24683430 Free PMC article.

10

The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin.

Wang B, Zeng L, Merillat SA, Fischer S, Ochaba J, Thompson LM, Barmada SJ, Scaglione KM, Paulson HL. Wang B, et al. Among authors: paulson hl. Neurobiol Dis. 2018 Jan;109(Pt A):127-136. doi: 10.1016/j.nbd.2017.10.002. Epub 2017 Oct 3. Neurobiol Dis. 2018. PMID: 28986324 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

268 results

Search Page

Filters