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Prions activate a p38 MAPK synaptotoxic signaling pathway.
Fang C, Wu B, Le NTT, Imberdis T, Mercer RCC, Harris DA. Fang C, et al. Among authors: imberdis t. PLoS Pathog. 2018 Sep 20;14(9):e1007283. doi: 10.1371/journal.ppat.1007283. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30235355 Free PMC article.
A Neuronal Culture System to Detect Prion Synaptotoxicity.
Fang C, Imberdis T, Garza MC, Wille H, Harris DA. Fang C, et al. Among authors: imberdis t. PLoS Pathog. 2016 May 26;12(5):e1005623. doi: 10.1371/journal.ppat.1005623. eCollection 2016 May. PLoS Pathog. 2016. PMID: 27227882 Free PMC article.
Identification of Anti-prion Compounds using a Novel Cellular Assay.
Imberdis T, Heeres JT, Yueh H, Fang C, Zhen J, Rich CB, Glicksman M, Beeler AB, Harris DA. Imberdis T, et al. J Biol Chem. 2016 Dec 9;291(50):26164-26176. doi: 10.1074/jbc.M116.745612. Epub 2016 Nov 1. J Biol Chem. 2016. PMID: 27803163 Free PMC article.
Low doses of bioherbicide favour prion aggregation and propagation in vivo.
Lafon PA, Imberdis T, Wang Y, Torrent J, Robitzer M, Huetter E, Alvarez-Martinez MT, Chevallier N, Givalois L, Desrumaux C, Liu J, Perrier V. Lafon PA, et al. Among authors: imberdis t. Sci Rep. 2018 May 23;8(1):8023. doi: 10.1038/s41598-018-25966-9. Sci Rep. 2018. PMID: 29795181 Free PMC article.
Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, Soldner F, Terry-Kantor E, Kim TE, Hofbauer HF, Becuwe M, Jaenisch R, Pincus D, Clish CB, Walther TC, Farese RV Jr, Srinivasan S, Welte MA, Kohlwein SD, Dettmer U, Lindquist S, Selkoe D. Fanning S, et al. Among authors: imberdis t. Mol Cell. 2019 Mar 7;73(5):1001-1014.e8. doi: 10.1016/j.molcel.2018.11.028. Epub 2018 Dec 4. Mol Cell. 2019. PMID: 30527540 Free PMC article.
22 results