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Page 1
Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction.
Sgrignani J, Cecchinato V, Fassi EMA, D'Agostino G, Garofalo M, Danelon G, Pedotti M, Simonelli L, Varani L, Grazioso G, Uguccioni M, Cavalli A. Sgrignani J, et al. Among authors: uguccioni m. J Med Chem. 2021 Sep 23;64(18):13439-13450. doi: 10.1021/acs.jmedchem.1c00852. Epub 2021 Sep 12. J Med Chem. 2021. PMID: 34510899 Free article.
Insight on the regulation of chemokine activities.
Cecchinato V, Uguccioni M. Cecchinato V, et al. Among authors: uguccioni m. J Leukoc Biol. 2018 Aug;104(2):295-300. doi: 10.1002/JLB.3MR0118-014R. Epub 2018 Apr 18. J Leukoc Biol. 2018. PMID: 29668065 Review.
Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization.
Cecchinato V, Bernasconi E, Speck RF, Proietti M, Sauermann U, D'Agostino G, Danelon G, Rezzonico Jost T, Grassi F, Raeli L, Schöni-Affolter F, Stahl-Hennig C, Uguccioni M; Swiss HIV Cohort Study. Cecchinato V, et al. Among authors: uguccioni m. J Immunol. 2017 Jan 1;198(1):184-195. doi: 10.4049/jimmunol.1600568. Epub 2016 Nov 28. J Immunol. 2017. PMID: 27895171 Free PMC article.
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4.
Collins PJ, McCully ML, Martínez-Muñoz L, Santiago C, Wheeldon J, Caucheteux S, Thelen S, Cecchinato V, Laufer JM, Purvanov V, Monneau YR, Lortat-Jacob H, Legler DF, Uguccioni M, Thelen M, Piguet V, Mellado M, Moser B. Collins PJ, et al. Among authors: uguccioni m. FASEB J. 2017 Jul;31(7):3084-3097. doi: 10.1096/fj.201700013R. Epub 2017 Mar 30. FASEB J. 2017. PMID: 28360196 Free PMC article.
Our findings provide new insights that will inform the development of novel therapeutics that target CXCR4 in a range of diseases, including cancer, autoimmunity, and HIV.-Collins, P. J., McCully, M. L., Martinez-Munoz, L., Santiago, C., Wheeldon, J., Caucheteux, S., Thele …
Our findings provide new insights that will inform the development of novel therapeutics that target CXCR4 in a range of diseases, including …
208 results