Melkani GC - Search Results

1

Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling.

Chandran S, Suggs JA, Wang BJ, Han A, Bhide S, Cryderman DE, Moore SA, Bernstein SI, Wallrath LL, Melkani GC. Chandran S, et al. Among authors: melkani gc. Hum Mol Genet. 2019 Feb 1;28(3):351-371. doi: 10.1093/hmg/ddy332. Hum Mol Genet. 2019. PMID: 30239736 Free PMC article.

2

Automated evaluation of cardiac contractile dynamics and aging prediction using machine learning in a Drosophila model.

Pant A, Melkani Y, Melkani GC. Pant A, et al. Among authors: melkani gc. Res Sq [Preprint]. 2023 Mar 21:rs.3.rs-2635745. doi: 10.21203/rs.3.rs-2635745/v1. Res Sq. 2023. Update in: Commun Biol. 2024 Jun 7;7(1):702. doi: 10.1038/s42003-024-06371-7 PMID: 36993511 Free PMC article. Updated. Preprint.

3

Diurnal expression of Dgat2 induced by time-restricted feeding maintains cardiac health in the Drosophila model of circadian disruption.

Guo Y, Abou Daya F, Le HD, Panda S, Melkani GC. Guo Y, et al. Among authors: melkani gc. Aging Cell. 2024 Jul;23(7):e14169. doi: 10.1111/acel.14169. Epub 2024 Apr 14. Aging Cell. 2024. PMID: 38616316 Free PMC article.

4

alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress.

Melkani GC, Cammarato A, Bernstein SI. Melkani GC, et al. J Mol Biol. 2006 May 5;358(3):635-45. doi: 10.1016/j.jmb.2006.02.043. Epub 2006 Mar 3. J Mol Biol. 2006. PMID: 16546210

5

Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head.

Bloemink MJ, Dambacher CM, Knowles AF, Melkani GC, Geeves MA, Bernstein SI. Bloemink MJ, et al. Among authors: melkani gc. J Mol Biol. 2009 Jun 19;389(4):707-21. doi: 10.1016/j.jmb.2009.04.036. Epub 2009 Apr 22. J Mol Biol. 2009. PMID: 19393244 Free PMC article.

6

Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability.

Kronert WA, Melkani GC, Melkani A, Bernstein SI. Kronert WA, et al. Among authors: melkani gc, melkani a. J Mol Biol. 2010 May 21;398(5):625-32. doi: 10.1016/j.jmb.2010.03.049. Epub 2010 Apr 1. J Mol Biol. 2010. PMID: 20362584 Free PMC article.

7

Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase.

Melkani GC, Lee CF, Cammarato A, Bernstein SI. Melkani GC, et al. Biochem Biophys Res Commun. 2010 May 28;396(2):317-22. doi: 10.1016/j.bbrc.2010.04.090. Epub 2010 Apr 18. Biochem Biophys Res Commun. 2010. PMID: 20403336 Free PMC article.

8

Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability.

Lee CF, Melkani GC, Yu Q, Suggs JA, Kronert WA, Suzuki Y, Hipolito L, Price MG, Epstein HF, Bernstein SI. Lee CF, et al. Among authors: melkani gc. J Cell Sci. 2011 Mar 1;124(Pt 5):699-705. doi: 10.1242/jcs.078964. Epub 2011 Feb 1. J Cell Sci. 2011. PMID: 21285246 Free PMC article.

9

Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities.

Bloemink MJ, Melkani GC, Dambacher CM, Bernstein SI, Geeves MA. Bloemink MJ, et al. Among authors: melkani gc. J Biol Chem. 2011 Aug 12;286(32):28435-43. doi: 10.1074/jbc.M111.258228. Epub 2011 Jun 16. J Biol Chem. 2011. PMID: 21680742 Free PMC article.

10

The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.

Melkani GC, Bodmer R, Ocorr K, Bernstein SI. Melkani GC, et al. PLoS One. 2011;6(7):e22579. doi: 10.1371/journal.pone.0022579. Epub 2011 Jul 25. PLoS One. 2011. PMID: 21799905 Free PMC article.

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