Goult BT - Search Results

1

Talin as a mechanosensitive signaling hub.

Goult BT, Yan J, Schwartz MA. Goult BT, et al. J Cell Biol. 2018 Nov 5;217(11):3776-3784. doi: 10.1083/jcb.201808061. Epub 2018 Sep 25. J Cell Biol. 2018. PMID: 30254032 Free PMC article. Review.

2

Mechanically operated signalling scaffolds.

Ball NJ, Barnett SFH, Goult BT. Ball NJ, et al. Among authors: goult bt. Biochem Soc Trans. 2024 Apr 24;52(2):517-527. doi: 10.1042/BST20221194. Biochem Soc Trans. 2024. PMID: 38572868 Free PMC article. Review.

3

Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation.

Goult BT, Bouaouina M, Elliott PR, Bate N, Patel B, Gingras AR, Grossmann JG, Roberts GC, Calderwood DA, Critchley DR, Barsukov IL. Goult BT, et al. EMBO J. 2010 Mar 17;29(6):1069-80. doi: 10.1038/emboj.2010.4. Epub 2010 Feb 11. EMBO J. 2010. PMID: 20150896 Free PMC article.

4

The domain structure of talin: residues 1815-1973 form a five-helix bundle containing a cryptic vinculin-binding site.

Goult BT, Gingras AR, Bate N, Barsukov IL, Critchley DR, Roberts GC. Goult BT, et al. FEBS Lett. 2010 Jun 3;584(11):2237-41. doi: 10.1016/j.febslet.2010.04.028. Epub 2010 Apr 20. FEBS Lett. 2010. PMID: 20399778 Free PMC article.

5

Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.

Kopp PM, Bate N, Hansen TM, Brindle NP, Praekelt U, Debrand E, Coleman S, Mazzeo D, Goult BT, Gingras AR, Pritchard CA, Critchley DR, Monkley SJ. Kopp PM, et al. Among authors: goult bt. Eur J Cell Biol. 2010 Sep;89(9):661-73. doi: 10.1016/j.ejcb.2010.05.003. Eur J Cell Biol. 2010. PMID: 20605055 Free PMC article.

6

RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.

Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GCK, Ballestrem C, Critchley DR, Barsukov IL. Goult BT, et al. J Biol Chem. 2013 Mar 22;288(12):8238-8249. doi: 10.1074/jbc.M112.438119. Epub 2013 Feb 6. J Biol Chem. 2013. PMID: 23389036 Free PMC article.

7

Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation.

Goult BT, Xu XP, Gingras AR, Swift M, Patel B, Bate N, Kopp PM, Barsukov IL, Critchley DR, Volkmann N, Hanein D. Goult BT, et al. J Struct Biol. 2013 Oct;184(1):21-32. doi: 10.1016/j.jsb.2013.05.014. Epub 2013 May 30. J Struct Biol. 2013. PMID: 23726984 Free PMC article.

8

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation.

Yao M, Goult BT, Chen H, Cong P, Sheetz MP, Yan J. Yao M, et al. Among authors: goult bt. Sci Rep. 2014 Apr 9;4:4610. doi: 10.1038/srep04610. Sci Rep. 2014. PMID: 24714394 Free PMC article.

9

The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering.

Ellis SJ, Lostchuck E, Goult BT, Bouaouina M, Fairchild MJ, López-Ceballos P, Calderwood DA, Tanentzapf G. Ellis SJ, et al. Among authors: goult bt. PLoS Genet. 2014 Nov 13;10(11):e1004756. doi: 10.1371/journal.pgen.1004756. eCollection 2014 Nov. PLoS Genet. 2014. PMID: 25393120 Free PMC article.

10

Talin Dependent Mechanosensitivity of Cell Focal Adhesions.

Yan J, Yao M, Goult BT, Sheetz MP. Yan J, et al. Among authors: goult bt. Cell Mol Bioeng. 2015;8(1):151-159. doi: 10.1007/s12195-014-0364-5. Epub 2014 Nov 4. Cell Mol Bioeng. 2015. PMID: 26097520 Free PMC article. Review.

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