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ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis.
Reese JM, Bruinsma ES, Nelson AW, Chernukhin I, Carroll JS, Li Y, Subramaniam M, Suman VJ, Negron V, Monroe DG, Ingle JN, Goetz MP, Hawse JR. Reese JM, et al. Among authors: bruinsma es. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9580-E9589. doi: 10.1073/pnas.1807751115. Epub 2018 Sep 26. Proc Natl Acad Sci U S A. 2018. PMID: 30257941 Free PMC article.
Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10.
Kim J, Shin S, Subramaniam M, Bruinsma E, Kim TD, Hawse JR, Spelsberg TC, Janknecht R. Kim J, et al. Biochem Biophys Res Commun. 2010 Oct 22;401(3):412-6. doi: 10.1016/j.bbrc.2010.09.068. Epub 2010 Sep 20. Biochem Biophys Res Commun. 2010. PMID: 20863814 Free PMC article.
TIEG1/KLF10 modulates Runx2 expression and activity in osteoblasts.
Hawse JR, Cicek M, Grygo SB, Bruinsma ES, Rajamannan NM, van Wijnen AJ, Lian JB, Stein GS, Oursler MJ, Subramaniam M, Spelsberg TC. Hawse JR, et al. Among authors: bruinsma es. PLoS One. 2011 Apr 29;6(4):e19429. doi: 10.1371/journal.pone.0019429. PLoS One. 2011. PMID: 21559363 Free PMC article.
TIEG and estrogen modulate SOST expression in the murine skeleton.
Subramaniam M, Pitel KS, Bruinsma ES, Monroe DG, Hawse JR. Subramaniam M, et al. Among authors: bruinsma es. J Cell Physiol. 2018 Apr;233(4):3540-3551. doi: 10.1002/jcp.26211. Epub 2017 Nov 24. J Cell Physiol. 2018. PMID: 29044507 Free PMC article.
Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities.
Kammoun M, Piquereau J, Nadal-Desbarats L, Même S, Beuvin M, Bonne G, Veksler V, Le Fur Y, Pouletaut P, Même W, Szeremeta F, Constans JM, Bruinsma ES, Nelson Holte MH, Najafova Z, Johnsen SA, Subramaniam M, Hawse JR, Bensamoun SF. Kammoun M, et al. Among authors: bruinsma es. Acta Physiol (Oxf). 2020 Mar;228(3):e13394. doi: 10.1111/apha.13394. Epub 2019 Oct 19. Acta Physiol (Oxf). 2020. PMID: 31560161 Free article.
Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues.
Hawse JR, Carter JM, Aspros KGM, Bruinsma ES, Koepplin JW, Negron V, Subramaniam M, Ingle JN, Rech KL, Goetz MP. Hawse JR, et al. Among authors: bruinsma es. Breast Cancer Res Treat. 2020 Jan;179(1):241-249. doi: 10.1007/s10549-019-05441-3. Epub 2019 Sep 30. Breast Cancer Res Treat. 2020. PMID: 31571071 Free PMC article.
Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer.
Jayaraman S, Hou X, Kuffel MJ, Suman VJ, Hoskin TL, Reinicke KE, Monroe DG, Kalari KR, Tang X, Zeldenrust MA, Cheng J, Bruinsma ES, Buhrow SA, McGovern RM, Safgren SL, Walden CA, Carter JM, Reid JM, Ingle JN, Ames MM, Hawse JR, Goetz MP. Jayaraman S, et al. Among authors: bruinsma es. Breast Cancer Res. 2020 May 19;22(1):51. doi: 10.1186/s13058-020-01286-7. Breast Cancer Res. 2020. PMID: 32430040 Free PMC article.
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