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MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage.
Lindeløv Vestergaard A, Heiner Bang-Berthelsen C, Fløyel T, Lucien Stahl J, Christen L, Taheri Sotudeh F, de Hemmer Horskjær P, Stensgaard Frederiksen K, Greek Kofod F, Bruun C, Adrian Berchtold L, Størling J, Regazzi R, Kaur S, Pociot F, Mandrup-Poulsen T. Lindeløv Vestergaard A, et al. Among authors: floyel t. PLoS One. 2018 Sep 27;13(9):e0203713. doi: 10.1371/journal.pone.0203713. eCollection 2018. PLoS One. 2018. PMID: 30260972 Free PMC article.
Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression.
Bergholdt R, Brorsson C, Palleja A, Berchtold LA, Fløyel T, Bang-Berthelsen CH, Frederiksen KS, Jensen LJ, Størling J, Pociot F. Bergholdt R, et al. Among authors: floyel t. Diabetes. 2012 Apr;61(4):954-62. doi: 10.2337/db11-1263. Epub 2012 Feb 16. Diabetes. 2012. PMID: 22344559 Free PMC article.
CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets.
Barbagallo D, Condorelli AG, Piro S, Parrinello N, Fløyel T, Ragusa M, Rabuazzo AM, Størling J, Purrello F, Di Pietro C, Purrello M. Barbagallo D, et al. Among authors: floyel t. Mol Biol Cell. 2014 Aug 15;25(16):2333-41. doi: 10.1091/mbc.E14-02-0703. Epub 2014 Jun 18. Mol Biol Cell. 2014. PMID: 24943845 Free PMC article.
CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.
Fløyel T, Brorsson C, Nielsen LB, Miani M, Bang-Berthelsen CH, Friedrichsen M, Overgaard AJ, Berchtold LA, Wiberg A, Poulsen P, Hansen L, Rosinger S, Boehm BO, Ram R, Nguyen Q, Mehta M, Morahan G, Concannon P, Bergholdt R, Nielsen JH, Reinheckel T, von Herrath M, Vaag A, Eizirik DL, Mortensen HB, Størling J, Pociot F. Fløyel T, et al. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10305-10. doi: 10.1073/pnas.1402571111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982147 Free PMC article. Clinical Trial.
20 results