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Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment.
Molinari A, Fallacara AL, Di Maria S, Zamperini C, Poggialini F, Musumeci F, Schenone S, Angelucci A, Colapietro A, Crespan E, Kissova M, Maga G, Botta M. Molinari A, et al. Among authors: musumeci f. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3454-3457. doi: 10.1016/j.bmcl.2018.09.024. Epub 2018 Sep 20. Bioorg Med Chem Lett. 2018. PMID: 30262428
Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.
Radi M, Dreassi E, Brullo C, Crespan E, Tintori C, Bernardo V, Valoti M, Zamperini C, Daigl H, Musumeci F, Carraro F, Naldini A, Filippi I, Maga G, Schenone S, Botta M. Radi M, et al. Among authors: musumeci f. J Med Chem. 2011 Apr 28;54(8):2610-26. doi: 10.1021/jm1012819. Epub 2011 Mar 28. J Med Chem. 2011. PMID: 21443205
An update on dual Src/Abl inhibitors.
Musumeci F, Schenone S, Brullo C, Botta M. Musumeci F, et al. Future Med Chem. 2012 Apr;4(6):799-822. doi: 10.4155/fmc.12.29. Future Med Chem. 2012. PMID: 22530642 Review.
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
Radi M, Evensen L, Dreassi E, Zamperini C, Caporicci M, Falchi F, Musumeci F, Schenone S, Lorens JB, Botta M. Radi M, et al. Among authors: musumeci f. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5579-83. doi: 10.1016/j.bmcl.2012.07.014. Epub 2012 Jul 13. Bioorg Med Chem Lett. 2012. PMID: 22853993
371 results