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The omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.
Hawcroft G, Volpato M, Marston G, Ingram N, Perry SL, Cockbain AJ, Race AD, Munarini A, Belluzzi A, Loadman PM, Coletta PL, Hull MA. Hawcroft G, et al. Among authors: marston g. Br J Pharmacol. 2012 Jul;166(5):1724-37. doi: 10.1111/j.1476-5381.2012.01882.x. Br J Pharmacol. 2012. PMID: 22300262 Free PMC article.
Reduced type II interleukin-4 receptor signalling drives initiation, but not progression, of colorectal carcinogenesis: evidence from transgenic mouse models and human case-control epidemiological observations.
Ingram N, Northwood EL, Perry SL, Marston G, Snowden H, Taylor JC, Scott N, Bishop DT, Coletta PL, Hull MA. Ingram N, et al. Among authors: marston g. Carcinogenesis. 2013 Oct;34(10):2341-9. doi: 10.1093/carcin/bgt222. Epub 2013 Jun 19. Carcinogenesis. 2013. PMID: 23784081 Free PMC article.
Changes in plasma chemokine C-C motif ligand 2 levels during treatment with eicosapentaenoic acid predict outcome in patients undergoing surgery for colorectal cancer liver metastasis.
Volpato M, Perry SL, Marston G, Ingram N, Cockbain AJ, Burghel H, Mann J, Lowes D, Wilson E, Droop A, Randerson-Moor J, Coletta PL, Hull MA. Volpato M, et al. Among authors: marston g. Oncotarget. 2016 May 10;7(19):28139-50. doi: 10.18632/oncotarget.8579. Oncotarget. 2016. PMID: 27058904 Free PMC article. Clinical Trial.
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