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Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib.
Buckley AM, Dunne MR, Morrissey ME, Kennedy SA, Nolan A, Davern M, Foley EK, Clarke N, Lysaght J, Ravi N, O'Toole D, MacCarthy F, Reynolds JV, Kennedy BN, O'Sullivan J. Buckley AM, et al. Among authors: clarke n. Sci Rep. 2020 Jul 21;10(1):12105. doi: 10.1038/s41598-020-68777-7. Sci Rep. 2020. PMID: 32694701 Free PMC article.
Impact of the inflammatory microenvironment on T-cell phenotype in the progression from reflux oesophagitis to Barrett oesophagus and oesophageal adenocarcinoma.
Kavanagh ME, Conroy MJ, Clarke NE, Gilmartin NT, O'Sullivan KE, Feighery R, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, O'Sullivan J, Lysaght J. Kavanagh ME, et al. Among authors: clarke ne. Cancer Lett. 2016 Jan 1;370(1):117-24. doi: 10.1016/j.canlet.2015.10.019. Epub 2015 Oct 28. Cancer Lett. 2016. PMID: 26519754
Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma.
Melo AM, O'Brien AM, Phelan JJ, Kennedy SA, Wood NAW, Veerapen N, Besra GS, Clarke NE, Foley EK, Ravi A, MacCarthy F, O'Toole D, Ravi N, Reynolds JV, Conroy MJ, Hogan AE, O'Sullivan J, Dunne MR. Melo AM, et al. Among authors: clarke ne. Front Immunol. 2019 Jul 10;10:1580. doi: 10.3389/fimmu.2019.01580. eCollection 2019. Front Immunol. 2019. PMID: 31354725 Free PMC article.
Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model.
Heeran AB, Berrigan HP, Buckley CE, Bottu HM, Prendiville O, Buckley AM, Clarke N, Donlon NE, Nugent TS, Durand M, Dunne C, Larkin JO, Mehigan B, McCormick P, Brennan L, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Among authors: clarke n. Transl Oncol. 2021 Jan;14(1):100882. doi: 10.1016/j.tranon.2020.100882. Epub 2020 Oct 23. Transl Oncol. 2021. PMID: 33129115 Free PMC article.
The Protein Secretome Is Altered in Rectal Cancer Tissue Compared to Normal Rectal Tissue, and Alterations in the Secretome Induce Enhanced Innate Immune Responses.
Heeran AB, Dunne MR, Morrissey ME, Buckley CE, Clarke N, Cannon A, Donlon NE, Nugent TS, Durand M, Dunne C, Larkin JO, Mehigan B, McCormick P, Lynam-Lennon N, O'Sullivan J. Heeran AB, et al. Among authors: clarke n. Cancers (Basel). 2021 Feb 2;13(3):571. doi: 10.3390/cancers13030571. Cancers (Basel). 2021. PMID: 33540635 Free PMC article.
Characterizing caspase-1 involvement during esophageal disease progression.
Barber G, Anand A, Katarzyna Oficjalska, Phelan JJ, Heeran AB, Flis E, Clarke NE, Watson JA, Strangmann J, Flood B, O'Neill H, O'Toole D, MacCarthy F, Ravi N, Reynolds JV, Kay EW, Quante M, O'Sullivan J, Creagh EM. Barber G, et al. Among authors: clarke ne. Cancer Immunol Immunother. 2020 Dec;69(12):2635-2649. doi: 10.1007/s00262-020-02650-4. Epub 2020 Jul 1. Cancer Immunol Immunother. 2020. PMID: 32613271 Free PMC article.
What GDPR and the Health Research Regulations (HRRs) mean for Ireland: "explicit consent"-a legal analysis.
Kirwan M, Mee B, Clarke N, Tanaka A, Manaloto L, Halpin E, Gibbons U, Cullen A, McGarrigle S, Connolly EM, Bennett K, Gaffney E, Flanagan C, Tier L, Flavin R, McElvaney NG. Kirwan M, et al. Among authors: clarke n. Ir J Med Sci. 2021 May;190(2):515-521. doi: 10.1007/s11845-020-02331-2. Epub 2020 Jul 30. Ir J Med Sci. 2021. PMID: 32728835 Free PMC article.
1,461 results