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A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily.
Korkut A, Zaidi S, Kanchi RS, Rao S, Gough NR, Schultz A, Li X, Lorenzi PL, Berger AC, Robertson G, Kwong LN, Datto M, Roszik J, Ling S, Ravikumar V, Manyam G, Rao A, Shelley S, Liu Y, Ju Z, Hansel D, de Velasco G, Pennathur A, Andersen JB, O'Rourke CJ, Ohshiro K, Jogunoori W, Nguyen BN, Li S, Osmanbeyoglu HU, Ajani JA, Mani SA, Houseman A, Wiznerowicz M, Chen J, Gu S, Ma W, Zhang J, Tong P, Cherniack AD, Deng C, Resar L; Cancer Genome Atlas Research Network; Weinstein JN, Mishra L, Akbani R. Korkut A, et al. Among authors: chen j. Cell Syst. 2018 Oct 24;7(4):422-437.e7. doi: 10.1016/j.cels.2018.08.010. Epub 2018 Sep 26. Cell Syst. 2018. PMID: 30268436 Free PMC article.
Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas.
Chen J, Raju GS, Jogunoori W, Menon V, Majumdar A, Chen JS, Gi YJ, Jeong YS, Phan L, Belkin M, Gu S, Kundra S, Mistry NA, Zhang J, Su X, Li S, Lin SH, Javle M, McMurray JS, Rahlfs TF, Mishra B, White J, Rashid A, Beauchemin N, Weston BR, Shafi MA, Stroehlein JR, Davila M, Akbani R, Weinstein JN, Wu X, Mishra L. Chen J, et al. Among authors: chen js. PLoS One. 2016 Apr 21;11(4):e0153933. doi: 10.1371/journal.pone.0153933. eCollection 2016. PLoS One. 2016. PMID: 27100181 Free PMC article.
Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation.
Chen J, Katz LH, Muñoz NM, Gu S, Shin JH, Jogunoori WS, Lee MH, Belkin MD, Kim SB, White JC, Andricovich J, Tzatsos A, Li S, Kim SS, Shetty K, Mishra B, Rashid A, Lee JS, Mishra L. Chen J, et al. Sci Rep. 2016 Jul 26;6:30217. doi: 10.1038/srep30217. Sci Rep. 2016. PMID: 27456065 Free PMC article.
Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway.
Chen J, Zaidi S, Rao S, Chen JS, Phan L, Farci P, Su X, Shetty K, White J, Zamboni F, Wu X, Rashid A, Pattabiraman N, Mazumder R, Horvath A, Wu RC, Li S, Xiao C, Deng CX, Wheeler DA, Mishra B, Akbani R, Mishra L. Chen J, et al. Among authors: chen js. Gastroenterology. 2018 Jan;154(1):195-210. doi: 10.1053/j.gastro.2017.09.007. Epub 2017 Sep 15. Gastroenterology. 2018. PMID: 28918914 Free PMC article.
Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling.
Chen J, Mitra A, Li S, Song S, Nguyen BN, Chen JS, Shin JH, Gough NR, Lin P, Obias V, He AR, Yao Z, Malta TM, Noushmehr H, Latham PS, Su X, Rashid A, Mishra B, Wu RC, Mishra L. Chen J, et al. Among authors: chen js. Cancer Res. 2020 May 1;80(9):1819-1832. doi: 10.1158/0008-5472.CAN-19-3116. Epub 2020 Mar 3. Cancer Res. 2020. PMID: 32127355 Free PMC article.
Targeting TGF-β signaling in cancer.
Katz LH, Li Y, Chen JS, Muñoz NM, Majumdar A, Chen J, Mishra L. Katz LH, et al. Among authors: chen j, chen js. Expert Opin Ther Targets. 2013 Jul;17(7):743-60. doi: 10.1517/14728222.2013.782287. Epub 2013 May 7. Expert Opin Ther Targets. 2013. PMID: 23651053 Free PMC article. Review.
Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability.
Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, Stroehlein JR, Chen J, Kim SS, Levin H, Machida K, Tsukamoto H, Michaely P, Tzatsos A, Mishra B, Amdur R, Mishra L. Chen J, et al. Hepatology. 2017 Feb;65(2):678-693. doi: 10.1002/hep.28927. Epub 2016 Dec 24. Hepatology. 2017. PMID: 28114741 Free PMC article.
ZC3H12A Expression in Different Stages of Colorectal Cancer.
Chen T, Du D, Chen J, Zhou P, Weinstein JN, Yao L, Liu Y. Chen T, et al. Among authors: chen j. Oncoscience. 2019 Apr 2;6(3-4):301-311. doi: 10.18632/oncoscience.480. eCollection 2019 Mar. Oncoscience. 2019. PMID: 31106233 Free PMC article.
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