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Page 1
Younger age of onset in familial amyotrophic lateral sclerosis is a result of pathogenic gene variants, rather than ascertainment bias.
Mehta PR, Jones AR, Opie-Martin S, Shatunov A, Iacoangeli A, Al Khleifat A, Smith BN, Topp S, Morrison KE, Shaw PJ, Shaw CE, Morgan S, Pittman A, Al-Chalabi A. Mehta PR, et al. Among authors: al chalabi a, al khleifat a. J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):268-271. doi: 10.1136/jnnp-2018-319089. Epub 2018 Sep 30. J Neurol Neurosurg Psychiatry. 2019. PMID: 30270202 Free PMC article.
Comparison of the King's and MiToS staging systems for ALS.
Fang T, Al Khleifat A, Stahl DR, Lazo La Torre C, Murphy C; Uk-Mnd LicalS; Young C, Shaw PJ, Leigh PN, Al-Chalabi A. Fang T, et al. Among authors: al chalabi a, al khleifat a. Amyotroph Lateral Scler Frontotemporal Degener. 2017 May;18(3-4):227-232. doi: 10.1080/21678421.2016.1265565. Epub 2017 Jan 5. Amyotroph Lateral Scler Frontotemporal Degener. 2017. PMID: 28054828 Free PMC article.
What causes amyotrophic lateral sclerosis?
Martin S, Al Khleifat A, Al-Chalabi A. Martin S, et al. Among authors: al chalabi a, al khleifat a. F1000Res. 2017 Mar 28;6:371. doi: 10.12688/f1000research.10476.1. eCollection 2017. F1000Res. 2017. PMID: 28408982 Free PMC article. Review.
A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK.
Morgan S, Shatunov A, Sproviero W, Jones AR, Shoai M, Hughes D, Al Khleifat A, Malaspina A, Morrison KE, Shaw PJ, Shaw CE, Sidle K, Orrell RW, Fratta P, Hardy J, Pittman A, Al-Chalabi A. Morgan S, et al. Among authors: al chalabi a, al khleifat a. Brain. 2017 Jun 1;140(6):1611-1618. doi: 10.1093/brain/awx082. Brain. 2017. PMID: 28430856 Free PMC article.
Detection of long repeat expansions from PCR-free whole-genome sequence data.
Dolzhenko E, van Vugt JJFA, Shaw RJ, Bekritsky MA, van Blitterswijk M, Narzisi G, Ajay SS, Rajan V, Lajoie BR, Johnson NH, Kingsbury Z, Humphray SJ, Schellevis RD, Brands WJ, Baker M, Rademakers R, Kooyman M, Tazelaar GHP, van Es MA, McLaughlin R, Sproviero W, Shatunov A, Jones A, Al Khleifat A, Pittman A, Morgan S, Hardiman O, Al-Chalabi A, Shaw C, Smith B, Neo EJ, Morrison K, Shaw PJ, Reeves C, Winterkorn L, Wexler NS; US–Venezuela Collaborative Research Group; Housman DE, Ng CW, Li AL, Taft RJ, van den Berg LH, Bentley DR, Veldink JH, Eberle MA. Dolzhenko E, et al. Among authors: al chalabi a, al khleifat a. Genome Res. 2017 Nov;27(11):1895-1903. doi: 10.1101/gr.225672.117. Epub 2017 Sep 8. Genome Res. 2017. PMID: 28887402 Free PMC article.
Stage at which riluzole treatment prolongs survival in patients with amyotrophic lateral sclerosis: a retrospective analysis of data from a dose-ranging study.
Fang T, Al Khleifat A, Meurgey JH, Jones A, Leigh PN, Bensimon G, Al-Chalabi A. Fang T, et al. Among authors: al chalabi a, al khleifat a. Lancet Neurol. 2018 May;17(5):416-422. doi: 10.1016/S1474-4422(18)30054-1. Epub 2018 Mar 7. Lancet Neurol. 2018. PMID: 29525492 Free PMC article. Clinical Trial.
A standard operating procedure for King's ALS clinical staging.
Balendra R, Al Khleifat A, Fang T, Al-Chalabi A. Balendra R, et al. Among authors: al chalabi a, al khleifat a. Amyotroph Lateral Scler Frontotemporal Degener. 2019 May;20(3-4):159-164. doi: 10.1080/21678421.2018.1556696. Epub 2019 Feb 18. Amyotroph Lateral Scler Frontotemporal Degener. 2019. PMID: 30773950 Free PMC article.
ALSgeneScanner: a pipeline for the analysis and interpretation of DNA sequencing data of ALS patients.
Iacoangeli A, Al Khleifat A, Sproviero W, Shatunov A, Jones AR, Opie-Martin S, Naselli E, Topp SD, Fogh I, Hodges A, Dobson RJ, Newhouse SJ, Al-Chalabi A. Iacoangeli A, et al. Among authors: al chalabi a, al khleifat a. Amyotroph Lateral Scler Frontotemporal Degener. 2019 May;20(3-4):207-215. doi: 10.1080/21678421.2018.1562553. Epub 2019 Mar 5. Amyotroph Lateral Scler Frontotemporal Degener. 2019. PMID: 30835568 Free PMC article.
Telomere length is greater in ALS than in controls: a whole genome sequencing study.
Al Khleifat A, Iacoangeli A, Shatunov A, Fang T, Sproviero W, Jones AR, Opie-Martin S, Morrison KE, Shaw PJ, Shaw CE, Powell JF, Dobson R, Newhouse SJ, Al-Chalabi A. Al Khleifat A, et al. Among authors: al chalabi a. Amyotroph Lateral Scler Frontotemporal Degener. 2019 May;20(3-4):229-234. doi: 10.1080/21678421.2019.1586951. Epub 2019 Apr 1. Amyotroph Lateral Scler Frontotemporal Degener. 2019. PMID: 30931641 Free PMC article.
59 results