Schoenfelder A - Search Results

1

Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists.

Wermuth CG, Bourguignon JJ, Schlewer G, Gies JP, Schoenfelder A, Melikian A, Bouchet MJ, Chantreux D, Molimard JC, Heaulme M, et al. Wermuth CG, et al. Among authors: schoenfelder a. J Med Chem. 1987 Feb;30(2):239-49. doi: 10.1021/jm00385a003. J Med Chem. 1987. PMID: 3027337

2

Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies.

Bourguignon JJ, Schoenfelder A, Schmitt M, Wermuth CG, Hechler V, Charlier B, Maitre M. Bourguignon JJ, et al. Among authors: schoenfelder a. J Med Chem. 1988 May;31(5):893-7. doi: 10.1021/jm00400a001. J Med Chem. 1988. PMID: 3361576

3

(2S,4S)-2-amino-4-(4,4-diphenylbut-1-yl)- pentane-1,5-dioic acid: a potent and selective antagonist for metabotropic glutamate receptors negatively linked to adenylate cyclase.

Wermuth CG, Mann A, Schoenfelder A, Wright RA, Johnson BG, Burnett JP, Mayne NG, Schoepp DD. Wermuth CG, et al. Among authors: schoenfelder a. J Med Chem. 1996 Feb 16;39(4):814-6. doi: 10.1021/jm9508144. J Med Chem. 1996. PMID: 8632404 No abstract available.

4

Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.

Solinas A, Faure H, Roudaut H, Traiffort E, Schoenfelder A, Mann A, Manetti F, Taddei M, Ruat M. Solinas A, et al. Among authors: schoenfelder a. J Med Chem. 2012 Feb 23;55(4):1559-71. doi: 10.1021/jm2013369. Epub 2012 Feb 10. J Med Chem. 2012. PMID: 22268551

5

A new method for the synthesis of chiral beta-branched alpha-amino acids.

Spangenberg T, Schoenfelder A, Breit B, Mann A. Spangenberg T, et al. Among authors: schoenfelder a. Org Lett. 2007 Sep 27;9(20):3881-4. doi: 10.1021/ol071305m. Epub 2007 Sep 6. Org Lett. 2007. PMID: 17803310

6

A general approach to aza-heterocycles by means of domino sequences driven by hydroformylation.

Airiau E, Spangenberg T, Girard N, Schoenfelder A, Salvadori J, Taddei M, Mann A. Airiau E, et al. Among authors: schoenfelder a. Chemistry. 2008;14(35):10938-48. doi: 10.1002/chem.200801795. Chemistry. 2008. PMID: 19009576

7

Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents.

Sautel F, Griffon N, Sokoloff P, Schwartz JC, Launay C, Simon P, Costentin J, Schoenfelder A, Garrido F, Mann A, et al. Sautel F, et al. Among authors: schoenfelder a. J Pharmacol Exp Ther. 1995 Dec;275(3):1239-46. J Pharmacol Exp Ther. 1995. PMID: 8531087

8

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

Hoch L, Faure H, Roudaut H, Schoenfelder A, Mann A, Girard N, Bihannic L, Ayrault O, Petricci E, Taddei M, Rognan D, Ruat M. Hoch L, et al. Among authors: schoenfelder a. FASEB J. 2015 May;29(5):1817-29. doi: 10.1096/fj.14-267849. Epub 2015 Jan 30. FASEB J. 2015. PMID: 25636740 Free PMC article.

9

Rhodium-catalyzed cyclohydrocarbonylation approach to the syntheses of enantiopure homokainoids.

Chiou WH, Schoenfelder A, Sun L, Mann A, Ojima I. Chiou WH, et al. Among authors: schoenfelder a. J Org Chem. 2007 Dec 7;72(25):9418-25. doi: 10.1021/jo070942n. Epub 2007 Nov 14. J Org Chem. 2007. PMID: 17999516

10

Potentiation of apple procyanidin-triggered apoptosis by the polyamine oxidase inactivator MDL 72527 in human colon cancer-derived metastatic cells.

Gossé F, Roussi S, Guyot S, Schoenfelder A, Mann A, Bergerat JP, Seiler N, Raul F. Gossé F, et al. Among authors: schoenfelder a. Int J Oncol. 2006 Aug;29(2):423-8. Int J Oncol. 2006. PMID: 16820885

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