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Brain-Permeant and -Impermeant Inhibitors of Fatty Acid Amide Hydrolase Synergize with the Opioid Analgesic Morphine to Suppress Chemotherapy-Induced Neuropathic Nociception Without Enhancing Effects of Morphine on Gastrointestinal Transit.
Slivicki RA, Saberi SA, Iyer V, Vemuri VK, Makriyannis A, Hohmann AG. Slivicki RA, et al. Among authors: makriyannis a. J Pharmacol Exp Ther. 2018 Dec;367(3):551-563. doi: 10.1124/jpet.118.252288. Epub 2018 Oct 1. J Pharmacol Exp Ther. 2018. PMID: 30275151 Free PMC article.
Structural requirements for cannabinoid receptor probes.
Thakur GA, Nikas SP, Li C, Makriyannis A. Thakur GA, et al. Among authors: makriyannis a. Handb Exp Pharmacol. 2005;(168):209-46. doi: 10.1007/3-540-26573-2_7. Handb Exp Pharmacol. 2005. PMID: 16596776 Review.
The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport.
Solinas M, Tanda G, Justinova Z, Wertheim CE, Yasar S, Piomelli D, Vadivel SK, Makriyannis A, Goldberg SR. Solinas M, et al. Among authors: makriyannis a. J Pharmacol Exp Ther. 2007 Apr;321(1):370-80. doi: 10.1124/jpet.106.114124. Epub 2007 Jan 8. J Pharmacol Exp Ther. 2007. PMID: 17210800
520 results