Cowley SM - Search Results

1

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo.

Kelly RDW, Chandru A, Watson PJ, Song Y, Blades M, Robertson NS, Jamieson AG, Schwabe JWR, Cowley SM. Kelly RDW, et al. Among authors: cowley sm. Sci Rep. 2018 Oct 2;8(1):14690. doi: 10.1038/s41598-018-32927-9. Sci Rep. 2018. PMID: 30279482 Free PMC article.

2

Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation.

Dovey OM, Foster CT, Cowley SM. Dovey OM, et al. Among authors: cowley sm. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8242-7. doi: 10.1073/pnas.1000478107. Epub 2010 Apr 19. Proc Natl Acad Sci U S A. 2010. PMID: 20404188 Free PMC article.

3

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.

Dovey OM, Foster CT, Conte N, Edwards SA, Edwards JM, Singh R, Vassiliou G, Bradley A, Cowley SM. Dovey OM, et al. Among authors: cowley sm. Blood. 2013 Feb 21;121(8):1335-44. doi: 10.1182/blood-2012-07-441949. Epub 2013 Jan 3. Blood. 2013. PMID: 23287868 Free PMC article.

4

The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts.

Kelly RD, Cowley SM. Kelly RD, et al. Among authors: cowley sm. Biochem Soc Trans. 2013 Jun;41(3):741-9. doi: 10.1042/BST20130010. Biochem Soc Trans. 2013. PMID: 23697933 Review.

5

Class I HDACs share a common mechanism of regulation by inositol phosphates.

Millard CJ, Watson PJ, Celardo I, Gordiyenko Y, Cowley SM, Robinson CV, Fairall L, Schwabe JW. Millard CJ, et al. Among authors: cowley sm. Mol Cell. 2013 Jul 11;51(1):57-67. doi: 10.1016/j.molcel.2013.05.020. Epub 2013 Jun 20. Mol Cell. 2013. PMID: 23791785 Free PMC article.

6

Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells.

Jamaladdin S, Kelly RD, O'Regan L, Dovey OM, Hodson GE, Millard CJ, Portolano N, Fry AM, Schwabe JW, Cowley SM. Jamaladdin S, et al. Among authors: cowley sm. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9840-5. doi: 10.1073/pnas.1321330111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958871 Free PMC article.

7

Recombinant protein expression for structural biology in HEK 293F suspension cells: a novel and accessible approach.

Portolano N, Watson PJ, Fairall L, Millard CJ, Milano CP, Song Y, Cowley SM, Schwabe JW. Portolano N, et al. Among authors: cowley sm. J Vis Exp. 2014 Oct 16;(92):e51897. doi: 10.3791/51897. J Vis Exp. 2014. PMID: 25349981 Free PMC article.

8

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates.

Watson PJ, Millard CJ, Riley AM, Robertson NS, Wright LC, Godage HY, Cowley SM, Jamieson AG, Potter BV, Schwabe JW. Watson PJ, et al. Among authors: cowley sm. Nat Commun. 2016 Apr 25;7:11262. doi: 10.1038/ncomms11262. Nat Commun. 2016. PMID: 27109927 Free PMC article.

9

Sin3A recruits Tet1 to the PAH1 domain via a highly conserved Sin3-Interaction Domain.

Chandru A, Bate N, Vuister GW, Cowley SM. Chandru A, et al. Among authors: cowley sm. Sci Rep. 2018 Oct 2;8(1):14689. doi: 10.1038/s41598-018-32942-w. Sci Rep. 2018. PMID: 30279502 Free PMC article.

10

Co-repressor, co-activator and general transcription factor: the many faces of the Sin3 histone deacetylase (HDAC) complex.

Adams GE, Chandru A, Cowley SM. Adams GE, et al. Among authors: cowley sm. Biochem J. 2018 Dec 14;475(24):3921-3932. doi: 10.1042/BCJ20170314. Biochem J. 2018. PMID: 30552170 Free PMC article. Review.

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