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Effects of safinamide on the glutamatergic striatal network in experimental Parkinson's disease.
Sciaccaluga M, Mazzocchetti P, Bastioli G, Ghiglieri V, Cardinale A, Mosci P, Caccia C, Keywood C, Melloni E, Padoani G, Vailati S, Picconi B, Calabresi P, Tozzi A. Sciaccaluga M, et al. Among authors: caccia c. Neuropharmacology. 2020 Jun 15;170:108024. doi: 10.1016/j.neuropharm.2020.108024. Epub 2020 Mar 3. Neuropharmacology. 2020. PMID: 32142791
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo.
Desaphy JF, Farinato A, Altamura C, De Bellis M, Imbrici P, Tarantino N, Caccia C, Melloni E, Padoani G, Vailati S, Keywood C, Carratù MR, De Luca A, Conte D, Pierno S. Desaphy JF, et al. Among authors: caccia c. Exp Neurol. 2020 Jun;328:113287. doi: 10.1016/j.expneurol.2020.113287. Epub 2020 Mar 20. Exp Neurol. 2020. PMID: 32205118
Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor.
Pisani L, Muncipinto G, Miscioscia TF, Nicolotti O, Leonetti F, Catto M, Caccia C, Salvati P, Soto-Otero R, Mendez-Alvarez E, Passeleu C, Carotti A. Pisani L, et al. Among authors: caccia c. J Med Chem. 2009 Nov 12;52(21):6685-706. doi: 10.1021/jm9010127. J Med Chem. 2009. PMID: 19810674
92 results