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Page 1
Senescent Cells Drive Frailty through Systemic Signals.
Lehmann J, Baar MP, de Keizer PLJ. Lehmann J, et al. Among authors: de keizer plj. Trends Mol Med. 2018 Nov;24(11):917-918. doi: 10.1016/j.molmed.2018.09.003. Epub 2018 Oct 3. Trends Mol Med. 2018. PMID: 30292430
Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling.
Kruiswijk F, Hasenfuss SC, Sivapatham R, Baar MP, Putavet D, Naipal KA, van den Broek NJ, Kruit W, van der Spek PJ, van Gent DC, Brenkman AB, Campisi J, Burgering BM, Hoeijmakers JH, de Keizer PL. Kruiswijk F, et al. Oncogene. 2016 Apr 28;35(17):2166-77. doi: 10.1038/onc.2015.282. Epub 2015 Aug 17. Oncogene. 2016. PMID: 26279295 Free PMC article.
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ. Baar MP, et al. Among authors: de keizer plj. Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031. Cell. 2017. PMID: 28340339 Free PMC article.
Maintenance and repair of an aging life cycle.
Baar MP, Van Willigenburg H, de Keizer PLJ. Baar MP, et al. Among authors: de keizer plj. Oncotarget. 2017 May 21;8(50):86985-86986. doi: 10.18632/oncotarget.18046. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152057 Free PMC article. No abstract available.
WNT/beta-catenin signalling interrupts a senescence-induction cascade in human mesenchymal stem cells that restricts their expansion.
Lehmann J, Narcisi R, Franceschini N, Chatzivasileiou D, Boer CG, Koevoet WJLM, Putavet D, Drabek D, van Haperen R, de Keizer PLJ, van Osch GJVM, Ten Berge D. Lehmann J, et al. Among authors: de keizer plj. Cell Mol Life Sci. 2022 Jan 20;79(2):82. doi: 10.1007/s00018-021-04035-x. Cell Mol Life Sci. 2022. PMID: 35048158 Free PMC article.
23 results