Wang H - Search Results

1

Design, synthesis and biological evaluation of 1,4-Diazobicylco[3.2.2]nonane derivatives as α7-Nicotinic acetylcholine receptor PET/CT imaging agents and agonists for Alzheimer's disease.

Wang S, Fang Y, Wang H, Gao H, Jiang G, Liu J, Xue Q, Qi Y, Cao M, Qiang B, Zhang H. Wang S, et al. Among authors: wang h. Eur J Med Chem. 2018 Nov 5;159:255-266. doi: 10.1016/j.ejmech.2018.09.064. Epub 2018 Sep 26. Eur J Med Chem. 2018. PMID: 30296684

2

Synthesis, biological evaluation, and molecular dynamics (MD) simulation studies of three novel F-18 labeled and focal adhesion kinase (FAK) targeted 5-bromo pyrimidines as radiotracers for tumor.

Fang Y, Wang D, Xu X, Liu J, Wu A, Li X, Xue Q, Wang H, Wang H, Zhang H. Fang Y, et al. Among authors: wang h, wang d. Eur J Med Chem. 2017 Feb 15;127:493-508. doi: 10.1016/j.ejmech.2017.01.015. Epub 2017 Jan 11. Eur J Med Chem. 2017. PMID: 28109944

3

Preparation, in vitro and in vivo evaluation, and molecular dynamics (MD) simulation studies of novel F-18 labeled tumor imaging agents targeting focal adhesion kinase (FAK).

Fang Y, Wang D, Xu X, Dava G, Liu J, Li X, Xue Q, Wang H, Zhang J, Zhang H. Fang Y, et al. Among authors: wang h, wang d. RSC Adv. 2018 Mar 14;8(19):10333-10345. doi: 10.1039/c8ra00652k. eCollection 2018 Mar 13. RSC Adv. 2018. PMID: 35540451 Free PMC article.

4

Initial evaluation of ^99m Tc-tricarbonyl-cyclopentadienyl fatty acids derivatives as SPECT tracers for myocardium.

Liu J, Wang H, Wang S, Xue Q, Wang D, Wang H, Zhang H. Liu J, et al. Among authors: wang h, wang d, wang s. J Labelled Comp Radiopharm. 2017 May 15;60(5):250-262. doi: 10.1002/jlcr.3497. Epub 2017 Apr 11. J Labelled Comp Radiopharm. 2017. PMID: 28185309

5

Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.

Xu YX, Wang H, Li XK, Dong SN, Liu WW, Gong Q, Wang TD, Tang Y, Zhu J, Li J, Zhang HY, Mao F. Xu YX, et al. Among authors: wang h, wang td. Eur J Med Chem. 2018 Jan 1;143:33-47. doi: 10.1016/j.ejmech.2017.08.025. Epub 2017 Aug 10. Eur J Med Chem. 2018. PMID: 29172081

6

2-Phenylcyclopropylmethylamine Derivatives as Dopamine D₂ Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation.

Yan W, Fan L, Yu J, Liu R, Wang H, Tan L, Wang S, Cheng J. Yan W, et al. Among authors: wang h, wang s. J Med Chem. 2021 Dec 9;64(23):17239-17258. doi: 10.1021/acs.jmedchem.1c01327. Epub 2021 Nov 19. J Med Chem. 2021. PMID: 34797051

7

The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression.

Li X, Li J, Huang Y, Gong Q, Fu Y, Xu Y, Huang J, You H, Zhang D, Zhang D, Mao F, Zhu J, Wang H, Zhang H, Li J. Li X, et al. Among authors: wang h. Eur J Med Chem. 2022 Feb 5;229:114045. doi: 10.1016/j.ejmech.2021.114045. Epub 2021 Dec 7. Eur J Med Chem. 2022. PMID: 34922191

8

Development of Multifunctional Pyrimidinylthiourea Derivatives as Potential Anti-Alzheimer Agents.

Li X, Wang H, Lu Z, Zheng X, Ni W, Zhu J, Fu Y, Lian F, Zhang N, Li J, Zhang H, Mao F. Li X, et al. Among authors: wang h. J Med Chem. 2016 Sep 22;59(18):8326-44. doi: 10.1021/acs.jmedchem.6b00636. Epub 2016 Sep 6. J Med Chem. 2016. PMID: 27552582

9

Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.

Liu W, Wang H, Li X, Xu Y, Zhang J, Wang W, Gong Q, Qiu X, Zhu J, Mao F, Zhang H, Li J. Liu W, et al. Among authors: wang h, wang w. Bioorg Med Chem. 2018 Jul 23;26(12):3117-3125. doi: 10.1016/j.bmc.2018.04.037. Epub 2018 Apr 18. Bioorg Med Chem. 2018. PMID: 29729987

10

Carbon-silicon switch led to the discovery of novel synthetic cannabinoids with therapeutic effects in a mouse model of multiple sclerosis.

Duan W, Sun Y, Wu M, Zhang Z, Zhang T, Wang H, Li F, Yang L, Xu Y, Liu ZJ, Hua T, Nie H, Cheng J. Duan W, et al. Among authors: wang h. Eur J Med Chem. 2021 Dec 15;226:113878. doi: 10.1016/j.ejmech.2021.113878. Epub 2021 Oct 5. Eur J Med Chem. 2021. PMID: 34634742

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