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Guide Swap enables genome-scale pooled CRISPR-Cas9 screening in human primary cells.
Ting PY, Parker AE, Lee JS, Trussell C, Sharif O, Luna F, Federe G, Barnes SW, Walker JR, Vance J, Gao MY, Klock HE, Clarkson S, Russ C, Miraglia LJ, Cooke MP, Boitano AE, McNamara P, Lamb J, Schmedt C, Snead JL. Ting PY, et al. Among authors: parker ae. Nat Methods. 2018 Nov;15(11):941-946. doi: 10.1038/s41592-018-0149-1. Epub 2018 Oct 8. Nat Methods. 2018. PMID: 30297964
Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease.
Miller AT, Dahlberg C, Sandberg ML, Wen BG, Beisner DR, Hoerter JA, Parker A, Schmedt C, Stinson M, Avis J, Cienfuegos C, McPate M, Tranter P, Gosling M, Groot-Kormelink PJ, Dawson J, Pan S, Tian SS, Seidel HM, Cooke MP. Miller AT, et al. PLoS One. 2015 Jun 29;10(6):e0131071. doi: 10.1371/journal.pone.0131071. eCollection 2015. PLoS One. 2015. PMID: 26121493 Free PMC article.
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain.
Beisner DR, Langerak P, Parker AE, Dahlberg C, Otero FJ, Sutton SE, Poirot L, Barnes W, Young MA, Niessen S, Wiltshire T, Bodendorf U, Martoglio B, Cravatt B, Cooke MP. Beisner DR, et al. Among authors: parker ae. J Exp Med. 2013 Jan 14;210(1):23-30. doi: 10.1084/jem.20121072. Epub 2012 Dec 24. J Exp Med. 2013. PMID: 23267013 Free PMC article.
119 results