Berubé G - Search Results

1

Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups.

Paquin A, Nolin F, Bouzriba C, Fortin S, Sevrioukova IF, Bérubé G. Paquin A, et al. Among authors: berube g. Steroids. 2024 Sep;209:109469. doi: 10.1016/j.steroids.2024.109469. Epub 2024 Jul 9. Steroids. 2024. PMID: 38992454

2

Investigating a new C2-symmetric testosterone dimer and its dihydrotestosterone analog: Synthesis, antiproliferative activity on prostate cancer cell lines and interaction with CYP3A4.

Paquin A, Fortin L, Girouard J, Reyes-Moreno C, Sevrioukova IF, Bérubé G. Paquin A, et al. Among authors: berube g. Eur J Med Chem. 2023 Mar 15;250:115222. doi: 10.1016/j.ejmech.2023.115222. Epub 2023 Feb 23. Eur J Med Chem. 2023. PMID: 36848848 Free PMC article.

3

Structural Characterization of Cis- and Trans-Pt(NH₃)₂Cl₂ Conjugations with Chitosan Nanoparticles.

Chanphai P, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. Molecules. 2022 Sep 23;27(19):6264. doi: 10.3390/molecules27196264. Molecules. 2022. PMID: 36234801 Free PMC article.

4

Chemical Synthesis and Biological Activities of Amaryllidaceae Alkaloid Norbelladine Derivatives and Precursors.

Girard MP, Karimzadegan V, Héneault M, Cloutier F, Bérubé G, Berthoux L, Mérindol N, Desgagné-Penix I. Girard MP, et al. Among authors: berube g. Molecules. 2022 Aug 31;27(17):5621. doi: 10.3390/molecules27175621. Molecules. 2022. PMID: 36080382 Free PMC article.

5

Innovative C₂-symmetric testosterone and androstenedione dimers: Design, synthesis, biological evaluation on prostate cancer cell lines and binding study to recombinant CYP3A4.

Paquin A, Oufqir Y, Sevrioukova IF, Reyes-Moreno C, Bérubé G. Paquin A, et al. Among authors: berube g. Eur J Med Chem. 2021 Aug 5;220:113496. doi: 10.1016/j.ejmech.2021.113496. Epub 2021 Apr 24. Eur J Med Chem. 2021. PMID: 33933755 Free PMC article.

6

Recent Advances in the Use of the Dimerization Strategy as a Means to Increase the Biological Potential of Natural or Synthetic Molecules.

Paquin A, Reyes-Moreno C, Bérubé G. Paquin A, et al. Among authors: berube g. Molecules. 2021 Apr 17;26(8):2340. doi: 10.3390/molecules26082340. Molecules. 2021. PMID: 33920597 Free PMC article. Review.

7

Locating the binding sites of two aminobenzoic acid derivatives on tRNA: drug binding efficacy and RNA structure.

Chanphai P, Cloutier F, Reyes-Moreno C, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. J Biomol Struct Dyn. 2022 Jan;40(1):130-135. doi: 10.1080/07391102.2020.1808076. Epub 2020 Aug 18. J Biomol Struct Dyn. 2022. PMID: 32811341

8

Binding efficacy of aminobenzoic acid derivatives with DNA duplex: drug binding sites and DNA structure and dynamics.

Chanphai P, Cloutier F, Reyes-Moreno C, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. J Biomol Struct Dyn. 2021 Apr;39(6):2278-2283. doi: 10.1080/07391102.2020.1740792. Epub 2020 Mar 24. J Biomol Struct Dyn. 2021. PMID: 32151202

9

Biomolecular study and conjugation of two para-aminobenzoic acid derivatives with serum proteins: drug binding efficacy and protein structural analysis.

Chanphai P, Cloutier F, Oufqir Y, Leclerc MF, Eiján AM, Reyes-Moreno C, Bérubé G, Tajmir-Riahi HA. Chanphai P, et al. Among authors: berube g. J Biomol Struct Dyn. 2021 Jan;39(1):79-90. doi: 10.1080/07391102.2020.1719889. Epub 2020 Feb 3. J Biomol Struct Dyn. 2021. PMID: 31980010

10

Molecular therapy with derivatives of amino benzoic acid inhibits tumor growth and metastasis in murine models of bladder cancer through inhibition of TNFα/NFΚB and iNOS/NO pathways.

Girouard J, Belgorosky D, Hamelin-Morrissette J, Boulanger V, D'Orio E, Ramla D, Perron R, Charpentier L, Van Themsche C, Eiján AM, Bérubé G, Reyes-Moreno C. Girouard J, et al. Among authors: berube g. Biochem Pharmacol. 2020 Jun;176:113778. doi: 10.1016/j.bcp.2019.113778. Epub 2019 Dec 24. Biochem Pharmacol. 2020. PMID: 31877271

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