Mårtensson LG - Search Results

1

Methylation of selenocysteine catalysed by thiopurine S-methyltransferase.

Urbančič D, Kotar A, Šmid A, Jukič M, Gobec S, Mårtensson LG, Plavec J, Mlinarič-Raščan I. Urbančič D, et al. Among authors: martensson lg. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):182-190. doi: 10.1016/j.bbagen.2018.10.002. Epub 2018 Oct 9. Biochim Biophys Acta Gen Subj. 2019. PMID: 30308221 Free article.

2

Structural characteristics determine the cause of the low enzyme activity of two thiopurine S-methyltransferase allelic variants: a biophysical characterization of TPMT*2 and TPMT*5.

Wennerstrand P, Dametto P, Hennig J, Klingstedt T, Skoglund K, Appell ML, Mårtensson LG. Wennerstrand P, et al. Among authors: martensson lg. Biochemistry. 2012 Jul 31;51(30):5912-20. doi: 10.1021/bi300377d. Epub 2012 Jul 16. Biochemistry. 2012. PMID: 22747506

3

In Vitro Protein Stability of Two Naturally Occurring Thiopurine S-Methyltransferase Variants: Biophysical Characterization of TPMT*6 and TPMT*8.

Wennerstrand P, Blissing A, Mårtensson LG. Wennerstrand P, et al. Among authors: martensson lg. ACS Omega. 2017 Aug 31;2(8):4991-4999. doi: 10.1021/acsomega.7b00801. Epub 2017 Aug 28. ACS Omega. 2017. PMID: 30023734 Free PMC article.

4

Role of an evolutionarily invariant serine for the stability of human carbonic anhydrase II.

Mårtensson LG, Jonsson BH, Andersson M, Kihlgren A, Bergenhem N, Carlsson U. Mårtensson LG, et al. Biochim Biophys Acta. 1992 Jan 9;1118(2):179-86. doi: 10.1016/0167-4838(92)90148-7. Biochim Biophys Acta. 1992. PMID: 1730037

5

Redesign of human carbonic anhydrase II for increased esterase activity and specificity towards esters with long acyl chains.

Höst G, Mårtensson LG, Jonsson BH. Höst G, et al. Among authors: martensson lg. Biochim Biophys Acta. 2006 Oct;1764(10):1601-6. doi: 10.1016/j.bbapap.2006.07.010. Epub 2006 Aug 17. Biochim Biophys Acta. 2006. PMID: 16996812 Free article.

6

Characterization of a novel sequence variant, TPMT*28, in the human thiopurine methyltransferase gene.

Appell ML, Wennerstrand P, Peterson C, Hertervig E, Mårtensson LG. Appell ML, et al. Among authors: martensson lg. Pharmacogenet Genomics. 2010 Nov;20(11):700-7. doi: 10.1097/FPC.0b013e3283402ee4. Pharmacogenet Genomics. 2010. PMID: 20881512

7

Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia.

Wennerstrand P, Mårtensson LG, Söderhäll S, Zimdahl A, Appell ML. Wennerstrand P, et al. Among authors: martensson lg. Eur J Clin Pharmacol. 2013 Sep;69(9):1641-9. doi: 10.1007/s00228-013-1521-9. Epub 2013 May 10. Eur J Clin Pharmacol. 2013. PMID: 23660772 Clinical Trial.

8

Comprehensive study of thiopurine methyltransferase genotype, phenotype, and genotype-phenotype discrepancies in Sweden.

Zimdahl Kahlin A, Helander S, Skoglund K, Söderkvist P, Mårtensson LG, Appell ML. Zimdahl Kahlin A, et al. Among authors: martensson lg. Biochem Pharmacol. 2019 Jun;164:263-272. doi: 10.1016/j.bcp.2019.04.020. Epub 2019 Apr 18. Biochem Pharmacol. 2019. PMID: 31005613 Free article.

9

Pharmacogenetic studies of thiopurine methyltransferase genotype-phenotype concordance and effect of methotrexate on thiopurine metabolism.

Zimdahl Kahlin A, Helander S, Wennerstrand P, Vikingsson S, Mårtensson LG, Appell ML. Zimdahl Kahlin A, et al. Among authors: martensson lg. Basic Clin Pharmacol Toxicol. 2021 Jan;128(1):52-65. doi: 10.1111/bcpt.13483. Epub 2020 Sep 14. Basic Clin Pharmacol Toxicol. 2021. PMID: 32865889 Free PMC article. Review.

10

One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability.

Iu YPH, Helander S, Kahlin AZ, Cheng CW, Shek CC, Leung MH, Wallner B, Mårtensson LG, Appell ML. Iu YPH, et al. Among authors: martensson lg. Sci Rep. 2017 May 2;7:46428. doi: 10.1038/srep46428. Sci Rep. 2017. PMID: 28462921 Free PMC article.

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