Lüpfert C - Search Results

1

A Novel PBPK Modeling Approach to Assess Cytochrome P450 Mediated Drug-Drug Interaction Potential of the Cytotoxic Prodrug Evofosfamide.

Lüpfert C, Dyroff M, von Richter O, Gallemann D, El Bawab S, Dolgos H, Jung D, Hecht S, Johne A. Lüpfert C, et al. CPT Pharmacometrics Syst Pharmacol. 2018 Dec;7(12):829-837. doi: 10.1002/psp4.12360. Epub 2018 Oct 31. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30311747 Free PMC article.

2

Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale.

Bonate PL, Wang T, Passier P, Bagchus W, Burt H, Lüpfert C, Abla N, Kovac J, Keiser J. Bonate PL, et al. Among authors: lupfert c. J Pharmacokinet Pharmacodyn. 2018 Oct;45(5):747-762. doi: 10.1007/s10928-018-9601-1. Epub 2018 Sep 14. J Pharmacokinet Pharmacodyn. 2018. PMID: 30218416 Free PMC article. Clinical Trial.

3

Platinum-based chemotherapy plus cetuximab first-line for Asian patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: Results of an open-label, single-arm, multicenter trial.

Guo Y, Shi M, Yang A, Feng J, Zhu X, Choi YJ, Hu G, Pan J, Hu C, Luo R, Zhang Y, Zhou L, Cheng Y, Lüpfert C, Cai J, Shi Y. Guo Y, et al. Among authors: lupfert c. Head Neck. 2015 Aug;37(8):1081-7. doi: 10.1002/hed.23707. Epub 2014 Sep 17. Head Neck. 2015. PMID: 24710768 Free article. Clinical Trial.

4

Refinement of the population pharmacokinetic model for the monoclonal antibody matuzumab: external model evaluation and simulations.

Kuester K, Kovar A, Lüpfert C, Brockhaus B, Kloft C. Kuester K, et al. Among authors: lupfert c. Clin Pharmacokinet. 2009;48(7):477-87. doi: 10.2165/11313400-000000000-00000. Clin Pharmacokinet. 2009. PMID: 19691369

5

Population pharmacokinetic data analysis of three phase I studies of matuzumab, a humanised anti-EGFR monoclonal antibody in clinical cancer development.

Kuester K, Kovar A, Lüpfert C, Brockhaus B, Kloft C. Kuester K, et al. Among authors: lupfert c. Br J Cancer. 2008 Mar 11;98(5):900-6. doi: 10.1038/sj.bjc.6604265. Epub 2008 Mar 4. Br J Cancer. 2008. PMID: 18319714 Free PMC article.

6

Phase I study of matuzumab in combination with 5-fluorouracil, leucovorin and cisplatin (PLF) in patients with advanced gastric and esophagogastric adenocarcinomas.

Trarbach T, Przyborek M, Schleucher N, Heeger S, Lüpfert C, Vanhoefer U. Trarbach T, et al. Among authors: lupfert c. Invest New Drugs. 2013 Jun;31(3):642-52. doi: 10.1007/s10637-012-9848-0. Epub 2012 Jul 5. Invest New Drugs. 2013. PMID: 22763610 Clinical Trial.

7

Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.

Lüpfert C, Reichel A. Lüpfert C, et al. Chem Biodivers. 2005 Nov;2(11):1462-86. doi: 10.1002/cbdv.200590119. Chem Biodivers. 2005. PMID: 17191947

8

Phase I study of epirubicin, cisplatin and capecitabine plus matuzumab in previously untreated patients with advanced oesophagogastric cancer.

Rao S, Starling N, Cunningham D, Benson M, Wotherspoon A, Lüpfert C, Kurek R, Oates J, Baselga J, Hill A. Rao S, et al. Among authors: lupfert c. Br J Cancer. 2008 Sep 16;99(6):868-74. doi: 10.1038/sj.bjc.6604622. Br J Cancer. 2008. PMID: 19238629 Free PMC article. Clinical Trial.

9

Assessment of the potential of the MET inhibitor tepotinib to affect the pharmacokinetics of CYP3A4 and P-gp substrates.

Yalkinoglu Ö, Becker A, Krebs-Brown A, Vetter C, Lüpfert C, Perrin D, Heuer J, Biedert H, Hirt S, Bytyqi A, Bachmann A, Strotmann R. Yalkinoglu Ö, et al. Among authors: lupfert c. Invest New Drugs. 2023 Aug;41(4):596-605. doi: 10.1007/s10637-023-01378-z. Epub 2023 Jul 6. Invest New Drugs. 2023. PMID: 37415001 Free PMC article.

10

The voltage-sensitive dye RH421 detects a Na⁺,K⁺-ATPase conformational change at the membrane surface.

Garcia A, Pratap PR, Lüpfert C, Cornelius F, Jacquemin D, Lev B, Allen TW, Clarke RJ. Garcia A, et al. Among authors: lupfert c. Biochim Biophys Acta Biomembr. 2017 May;1859(5):813-823. doi: 10.1016/j.bbamem.2017.01.022. Epub 2017 Jan 20. Biochim Biophys Acta Biomembr. 2017. PMID: 28115116 Free article.

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