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The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health.
Luo C, Yang Q, Liu Y, Zhou S, Jiang J, Reiter RJ, Bhattacharya P, Cui Y, Yang H, Ma H, Yao J, Lawler SE, Zhang X, Fu J, Rozental R, Aly H, Johnson MD, Chiocca EA, Wang X. Luo C, et al. Among authors: zhang x. Free Radic Biol Med. 2019 Jan;130:215-233. doi: 10.1016/j.freeradbiomed.2018.10.402. Epub 2018 Oct 11. Free Radic Biol Med. 2019. PMID: 30315933 Review.
N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.
Zhou H, Wang J, Jiang J, Stavrovskaya IG, Li M, Li W, Wu Q, Zhang X, Luo C, Zhou S, Sirianni AC, Sarkar S, Kristal BS, Friedlander RM, Wang X. Zhou H, et al. Among authors: zhang x. J Neurosci. 2014 Feb 19;34(8):2967-78. doi: 10.1523/JNEUROSCI.1948-13.2014. J Neurosci. 2014. PMID: 24553937 Free PMC article.
Tartary buckwheat extract alleviates alcohol-induced acute and chronic liver injuries through the inhibition of oxidative stress and mitochondrial cell death pathway.
Yang Q, Luo C, Zhang X, Liu Y, Wang Z, Cacciamani P, Shi J, Cui Y, Wang C, Sinha B, Peng B, Tong G, Das G, Shah E, Gao Y, Li W, Tu Y, Qian D, Shah K, Akbar M, Zhou S, Song BJ, Wang X. Yang Q, et al. Among authors: zhang x. Am J Transl Res. 2020 Jan 15;12(1):70-89. eCollection 2020. Am J Transl Res. 2020. PMID: 32051738 Free PMC article.
The MT1 receptor as the target of ramelteon neuroprotection in ischemic stroke.
Zhang X, Peng B, Zhang S, Wang J, Yuan X, Peled S, Chen W, Ding J, Li W, Zhang A, Wu Q, Stavrovskaya IG, Luo C, Sinha B, Tu Y, Yuan X, Li M, Liu S, Fu J, Aziz-Sultan A, Kristal BS, Alterovitz G, Du R, Zhou S, Wang X. Zhang X, et al. Among authors: zhang s, zhang a. J Pineal Res. 2024 Jan;76(1):e12925. doi: 10.1111/jpi.12925. Epub 2023 Nov 20. J Pineal Res. 2024. PMID: 37986632
179,997 results
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