Xu X - Search Results

1

Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model.

Luo F, Xie Y, Wang Z, Huang J, Tan Q, Sun X, Li F, Li C, Liu M, Zhang D, Xu M, Su N, Ni Z, Jiang W, Chang J, Chen H, Chen S, Xu X, Deng C, Wang Z, Du X, Chen L. Luo F, et al. Among authors: xu m, xu x. Mol Ther Nucleic Acids. 2018 Dec 7;13:291-302. doi: 10.1016/j.omtn.2018.09.012. Epub 2018 Sep 22. Mol Ther Nucleic Acids. 2018. PMID: 30321816 Free PMC article.

2

Generation and analysis of Brca1 conditional knockout mice.

Deng CX, Xu X. Deng CX, et al. Among authors: xu x. Methods Mol Biol. 2004;280:185-200. doi: 10.1385/1-59259-788-2:185. Methods Mol Biol. 2004. PMID: 15187254

3

A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.

Yin L, Du X, Li C, Xu X, Chen Z, Su N, Zhao L, Qi H, Li F, Xue J, Yang J, Jin M, Deng C, Chen L. Yin L, et al. Among authors: xu x. Bone. 2008 Apr;42(4):631-43. doi: 10.1016/j.bone.2007.11.019. Epub 2008 Jan 31. Bone. 2008. PMID: 18242159

4

Generation of Fgfr3 conditional knockout mice.

Su N, Xu X, Li C, He Q, Zhao L, Li C, Chen S, Luo F, Yi L, Du X, Huang H, Deng C, Chen L. Su N, et al. Among authors: xu x. Int J Biol Sci. 2010 Jun 15;6(4):327-32. doi: 10.7150/ijbs.6.327. Int J Biol Sci. 2010. PMID: 20582225 Free PMC article.

5

"DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint.

Masuda T, Xu X, Dimitriadis EK, Lahusen T, Deng CX. Masuda T, et al. Among authors: xu x. Int J Biol Sci. 2016 Jan 1;12(2):133-43. doi: 10.7150/ijbs.14242. eCollection 2016. Int J Biol Sci. 2016. PMID: 26884712 Free PMC article.

6

Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin.

Chisholm CL, Wang H, Wong AH, Vazquez-Ortiz G, Chen W, Xu X, Deng CX. Chisholm CL, et al. Among authors: xu x. Oncotarget. 2016 Dec 20;7(51):84439-84452. doi: 10.18632/oncotarget.12992. Oncotarget. 2016. PMID: 27806319 Free PMC article.

7

WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance.

Zheng H, Shao F, Martin S, Xu X, Deng CX. Zheng H, et al. Among authors: xu x. Sci Rep. 2017 Mar 6;7:43517. doi: 10.1038/srep43517. Sci Rep. 2017. PMID: 28262781 Free PMC article.

8

Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation.

Xu W, Luo F, Wang Q, Tan Q, Huang J, Zhou S, Wang Z, Sun X, Kuang L, Jin M, Su N, Jiang W, Chen L, Qi H, Zhu Y, Chen B, Chen H, Chen S, Gao Y, Xu X, Deng C, Chen L, Xie Y, Du X. Xu W, et al. Among authors: xu x. J Bone Miner Res. 2017 Nov;32(11):2194-2206. doi: 10.1002/jbmr.3204. Epub 2017 Sep 12. J Bone Miner Res. 2017. PMID: 28650109 Free article.

9

BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis.

Lahusen TJ, Kim SJ, Miao K, Huang Z, Xu X, Deng CX. Lahusen TJ, et al. Among authors: xu x. Oncogene. 2018 Apr;37(17):2343-2350. doi: 10.1038/s41388-018-0127-1. Epub 2018 Feb 14. Oncogene. 2018. PMID: 29440709

10

Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice.

Miao K, Zhang X, Su SM, Zeng J, Huang Z, Chan UI, Xu X, Deng CX. Miao K, et al. Among authors: xu x. J Biol Chem. 2019 Jan 25;294(4):1142-1151. doi: 10.1074/jbc.RA118.006496. Epub 2018 Nov 28. J Biol Chem. 2019. PMID: 30487289 Free PMC article.

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