Furlong E - Search Results

1

Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles.

Kummari LK, Butler MS, Furlong E, Blundell R, Nouwens A, Silva AB, Kappler U, Fraser JA, Kobe B, Cooper MA, Robertson AAB. Kummari LK, et al. Among authors: furlong e. Bioorg Med Chem. 2018 Nov 1;26(20):5408-5419. doi: 10.1016/j.bmc.2018.09.004. Epub 2018 Sep 5. Bioorg Med Chem. 2018. PMID: 30322754

2

Disulfide isomerase activity of the dynamic, trimeric Proteus mirabilis ScsC protein is primed by the tandem immunoglobulin-fold domain of ScsB.

Furlong EJ, Choudhury HG, Kurth F, Duff AP, Whitten AE, Martin JL. Furlong EJ, et al. J Biol Chem. 2018 Apr 20;293(16):5793-5805. doi: 10.1074/jbc.RA118.001860. Epub 2018 Feb 28. J Biol Chem. 2018. PMID: 29491145 Free PMC article.

3

A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.

Furlong EJ, Lo AW, Kurth F, Premkumar L, Totsika M, Achard MES, Halili MA, Heras B, Whitten AE, Choudhury HG, Schembri MA, Martin JL. Furlong EJ, et al. Nat Commun. 2017 Jul 19;8:16065. doi: 10.1038/ncomms16065. Nat Commun. 2017. PMID: 28722010 Free PMC article.

4

Engineered variants provide new insight into the structural properties important for activity of the highly dynamic, trimeric protein disulfide isomerase ScsC from Proteus mirabilis.

Furlong EJ, Kurth F, Premkumar L, Whitten AE, Martin JL. Furlong EJ, et al. Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):296-307. doi: 10.1107/S2059798319000081. Epub 2019 Feb 26. Acta Crystallogr D Struct Biol. 2019. PMID: 30950400 Free PMC article.

5

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity.

Petit GA, Hong Y, Djoko KY, Whitten AE, Furlong EJ, McCoy AJ, Gulbis JM, Totsika M, Martin JL, Halili MA. Petit GA, et al. Among authors: furlong ej. Acta Crystallogr D Struct Biol. 2022 Mar 1;78(Pt 3):337-352. doi: 10.1107/S2059798322000729. Epub 2022 Feb 21. Acta Crystallogr D Struct Biol. 2022. PMID: 35234148 Free PMC article.

6

Author Correction: A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.

Furlong EJ, Lo AW, Kurth F, Premkumar L, Totsika M, Achard MES, Halili MA, Heras B, Whitten AE, Choudhury HG, Schembri MA, Martin JL. Furlong EJ, et al. Nat Commun. 2019 Mar 1;10(1):976. doi: 10.1038/s41467-019-08920-9. Nat Commun. 2019. PMID: 30824772 Free PMC article.

7

Expression, purification and characterization of the suppressor of copper sensitivity (Scs) B membrane protein from Proteus mirabilis.

Jarrott RJ, Furlong EJ, Petit GA, Drew D, Martin JL, Halili MA. Jarrott RJ, et al. Protein Expr Purif. 2022 May;193:106047. doi: 10.1016/j.pep.2022.106047. Epub 2022 Jan 11. Protein Expr Purif. 2022. PMID: 35026386 Free article.

8

Structural and Biochemical Characterization of Chlamydia trachomatis DsbA Reveals a Cysteine-Rich and Weakly Oxidising Oxidoreductase.

Christensen S, Grøftehauge MK, Byriel K, Huston WM, Furlong E, Heras B, Martin JL, McMahon RM. Christensen S, et al. Among authors: furlong e. PLoS One. 2016 Dec 28;11(12):e0168485. doi: 10.1371/journal.pone.0168485. eCollection 2016. PLoS One. 2016. PMID: 28030602 Free PMC article.

9

Disarming Burkholderia pseudomallei: structural and functional characterization of a disulfide oxidoreductase (DsbA) required for virulence in vivo.

Ireland PM, McMahon RM, Marshall LE, Halili M, Furlong E, Tay S, Martin JL, Sarkar-Tyson M. Ireland PM, et al. Among authors: furlong e. Antioxid Redox Signal. 2014 Feb 1;20(4):606-17. doi: 10.1089/ars.2013.5375. Epub 2013 Sep 20. Antioxid Redox Signal. 2014. PMID: 23901809 Free PMC article.

10

Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.

Johnson S, Fong YH, Deme JC, Furlong EJ, Kuhlen L, Lea SM. Johnson S, et al. Nat Microbiol. 2020 Jul;5(7):966-975. doi: 10.1038/s41564-020-0703-3. Epub 2020 Apr 13. Nat Microbiol. 2020. PMID: 32284565 Free PMC article.

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