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The radiosensitizing effect of immunoadjuvant OM-174 requires cooperation between immune and tumor cells through interferon-gamma and inducible nitric oxide synthase.
De Ridder M, Verovski VN, Chiavaroli C, Van den Berge DL, Monsaert C, Law K, Storme GA. De Ridder M, et al. Among authors: law k. Int J Radiat Oncol Biol Phys. 2006 Dec 1;66(5):1473-80. doi: 10.1016/j.ijrobp.2006.07.1381. Epub 2006 Oct 23. Int J Radiat Oncol Biol Phys. 2006. PMID: 17056198
Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.
Jiang H, De Ridder M, Verovski VN, Sonveaux P, Jordan BF, Law K, Monsaert C, Van den Berge DL, Verellen D, Feron O, Gallez B, Storme GA. Jiang H, et al. Among authors: law k. Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1520-7. doi: 10.1016/j.ijrobp.2009.10.047. Int J Radiat Oncol Biol Phys. 2010. PMID: 20338478
Hepatocytes determine the hypoxic microenvironment and radiosensitivity of colorectal cancer cells through production of nitric oxide that targets mitochondrial respiration.
Jiang H, Verovski VN, Leonard W, Law KL, Vermeersch M, Storme G, Van den Berge D, Gevaert T, Sermeus A, De Ridder M. Jiang H, et al. Int J Radiat Oncol Biol Phys. 2013 Mar 1;85(3):820-7. doi: 10.1016/j.ijrobp.2012.07.2359. Epub 2012 Sep 11. Int J Radiat Oncol Biol Phys. 2013. PMID: 22975619
Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells.
de Mey S, Dufait I, Jiang H, Corbet C, Wang H, Van De Gucht M, Kerkhove L, Law KL, Vandenplas H, Gevaert T, Feron O, De Ridder M. de Mey S, et al. Int J Mol Sci. 2020 Dec 9;21(24):9367. doi: 10.3390/ijms21249367. Int J Mol Sci. 2020. PMID: 33316932 Free PMC article.
733 results