Stokes C - Search Results

1

Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation.

Quadri M, Silnović A, Matera C, Horenstein NA, Stokes C, De Amici M, Papke RL, Dallanoce C. Quadri M, et al. Among authors: stokes c. Eur J Med Chem. 2018 Dec 5;160:207-228. doi: 10.1016/j.ejmech.2018.10.015. Epub 2018 Oct 11. Eur J Med Chem. 2018. PMID: 30342362 Free PMC article.

2

Antagonist activities of mecamylamine and nicotine show reciprocal dependence on beta subunit sequence in the second transmembrane domain.

Webster JC, Francis MM, Porter JK, Robinson G, Stokes C, Horenstein B, Papke RL. Webster JC, et al. Among authors: stokes c. Br J Pharmacol. 1999 Jul;127(6):1337-48. doi: 10.1038/sj.bjp.0702686. Br J Pharmacol. 1999. PMID: 10455283 Free PMC article.

3

The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors.

Stokes C, Papke JK, Horenstein NA, Kem WR, McCormack TJ, Papke RL. Stokes C, et al. Mol Pharmacol. 2004 Jul;66(1):14-24. doi: 10.1124/mol.66.1.14. Mol Pharmacol. 2004. PMID: 15213292

4

Rhesus monkey alpha7 nicotinic acetylcholine receptors: comparisons to human alpha7 receptors expressed in Xenopus oocytes.

Papke RL, McCormack TJ, Jack BA, Wang D, Bugaj-Gaweda B, Schiff HC, Buhr JD, Waber AJ, Stokes C. Papke RL, et al. Among authors: stokes c. Eur J Pharmacol. 2005 Nov 7;524(1-3):11-8. doi: 10.1016/j.ejphar.2005.08.043. Epub 2005 Nov 2. Eur J Pharmacol. 2005. PMID: 16266703

5

Reversal of agonist selectivity by mutations of conserved amino acids in the binding site of nicotinic acetylcholine receptors.

Horenstein NA, McCormack TJ, Stokes C, Ren K, Papke RL. Horenstein NA, et al. Among authors: stokes c. J Biol Chem. 2007 Feb 23;282(8):5899-909. doi: 10.1074/jbc.M609202200. Epub 2006 Dec 21. J Biol Chem. 2007. PMID: 17189260 Free article.

6

Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras.

Papke RL, Dwoskin LP, Crooks PA, Zheng G, Zhang Z, McIntosh JM, Stokes C. Papke RL, et al. Among authors: stokes c. Neuropharmacology. 2008 Jun;54(8):1189-200. doi: 10.1016/j.neuropharm.2008.03.010. Epub 2008 Mar 28. Neuropharmacology. 2008. PMID: 18448138 Free PMC article.

7

Modeling binding modes of alpha7 nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding.

Huang X, Zheng F, Stokes C, Papke RL, Zhan CG. Huang X, et al. Among authors: stokes c. J Med Chem. 2008 Oct 23;51(20):6293-302. doi: 10.1021/jm800607u. Epub 2008 Oct 1. J Med Chem. 2008. PMID: 18826295 Free PMC article.

8

Differential regulation of receptor activation and agonist selectivity by highly conserved tryptophans in the nicotinic acetylcholine receptor binding site.

Williams DK, Stokes C, Horenstein NA, Papke RL. Williams DK, et al. Among authors: stokes c. J Pharmacol Exp Ther. 2009 Jul;330(1):40-53. doi: 10.1124/jpet.109.151225. Epub 2009 Apr 1. J Pharmacol Exp Ther. 2009. PMID: 19339660 Free PMC article.

9

Working with OpusXpress: methods for high volume oocyte experiments.

Papke RL, Stokes C. Papke RL, et al. Among authors: stokes c. Methods. 2010 May;51(1):121-33. doi: 10.1016/j.ymeth.2010.01.012. Epub 2010 Jan 18. Methods. 2010. PMID: 20085813 Free PMC article.

10

Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper.

Papke RL, Stokes C, Williams DK, Wang J, Horenstein NA. Papke RL, et al. Among authors: stokes c. Neuropharmacology. 2011 Jan;60(1):159-71. doi: 10.1016/j.neuropharm.2010.07.014. Epub 2010 Jul 27. Neuropharmacology. 2011. PMID: 20650284 Free PMC article.

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