Keane KA - Search Results

1

The Effect of Diet-induced Obesity on Toxicological Parameters in the Polygenic Sprague-Dawley Rat Model.

Rojas JM, Bolze F, Thorup I, Nowak J, Dalsgaard CM, Skydsgaard M, Berthelsen LO, Keane KA, Søeborg H, Sjögren I, Jensen JT, Fels JJ, Offenberg HK, Andersen LW, Dalgaard M. Rojas JM, et al. Among authors: keane ka. Toxicol Pathol. 2018 Oct;46(7):777-798. doi: 10.1177/0192623318803557. Epub 2018 Oct 22. Toxicol Pathol. 2018. PMID: 30343647

2

Scientific and Regulatory Policy Committee (SRPC) Points to Consider: Histopathology Evaluation of the Pubertal Development and Thyroid Function Assay (OPPTS 890.1450, OPPTS 890.1500) in Rats to Screen for Endocrine Disruptors.

Keane KA, Parker GA, Regan KS, Picut C, Dixon D, Creasy D, Giri D, Hukkanen RR. Keane KA, et al. Toxicol Pathol. 2015 Dec;43(8):1047-63. doi: 10.1177/0192623315579943. Epub 2015 May 6. Toxicol Pathol. 2015. PMID: 25948506 Free PMC article.

3

A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.

Lauritzen B, Bjelke M, Björkdahl O, Bloem E, Keane K, Kjalke M, Rossen M, Lippert SL, Weldingh KN, Skydsgaard M, Kjellev S. Lauritzen B, et al. J Thromb Haemost. 2022 Jun;20(6):1312-1324. doi: 10.1111/jth.15682. Epub 2022 Mar 6. J Thromb Haemost. 2022. PMID: 35191180 Free PMC article.

4

Opinion on Current Use of Non-Blinded Versus Blinded Histopathologic Evaluation in Animal Toxicity Studies.

Bolon B, Caverly Rae JM, Colman K, Francke S, Jensen K, Keane K, McInnes EF, Nakano-Ito K, Perry R, Polack E, Regan KS, Romeike A, Young JK, Galbreath EJ. Bolon B, et al. Toxicol Pathol. 2020 Jun;48(4):549-559. doi: 10.1177/0192623320920590. Epub 2020 Apr 29. Toxicol Pathol. 2020. PMID: 32347786

5

Adversity Considerations for Thyroid Follicular Cell Hypertrophy and Hyperplasia in Nonclinical Toxicity Studies: Results From the 6th ESTP International Expert Workshop.

Huisinga M, Bertrand L, Chamanza R, Damiani I, Engelhardt J, Francke S, Freyberger A, Harada T, Harleman J, Kaufmann W, Keane K, Köhrle J, Lenz B, Marty MS, Melching-Kollmuss S, Palazzi X, Pohlmeyer-Esch G, Popp A, Rosol TJ, Strauss V, Van den Brink-Knol H, Wood CE, Yoshida M. Huisinga M, et al. Toxicol Pathol. 2020 Dec;48(8):920-938. doi: 10.1177/0192623320972009. Toxicol Pathol. 2020. PMID: 33334259

6

Characterization of the Nonendocrine Cell Populations in Human Embryonic Stem Cell-Derived (hESC) Islet-Like Clusters Posttransplantation.

Jensen NK, Ingvorsen C, Petersen DR, Pereira MJ, Lu TTH, Alsted TJ, Kirkegaard JS, Keane KA. Jensen NK, et al. Among authors: keane ka. Toxicol Pathol. 2021 Oct;49(7):1269-1287. doi: 10.1177/01926233211036395. Epub 2021 Sep 23. Toxicol Pathol. 2021. PMID: 34555946

7

Scientific and Regulatory Policy Committee Best Practices: Recommended ("Best") Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies.

Bolon B, Francke S, Caverly Rae JM, Polack E, Regan KS, McInnes EF, Young JK, Keane K, Perry R, Romeike A, Colman K, Jensen K, Nakano-Ito K, Galbreath EJ. Bolon B, et al. Toxicol Pathol. 2022 Dec;50(8):930-941. doi: 10.1177/01926233221135563. Epub 2022 Nov 14. Toxicol Pathol. 2022. PMID: 36377245

8

Scientific and Regulatory Policy Committee Points to Consider for Medical Device Implant Site Evaluation in Nonclinical Studies.

O'Brien MT, Schuh JCL, Wancket LM, Cramer SD, Funk KA, Jackson ND, Kannan K, Keane K, Nyska A, Rousselle SD, Schucker A, Thomas VS, Tunev S. O'Brien MT, et al. Among authors: keane k. Toxicol Pathol. 2022 Jun;50(4):512-530. doi: 10.1177/01926233221103202. Epub 2022 Jun 28. Toxicol Pathol. 2022. PMID: 35762822

9

Neurooncology.

Bradley AE, Keane K. Bradley AE, et al. Toxicol Pathol. 2011 Jan;39(1):124-8. doi: 10.1177/0192623310389477. Epub 2010 Dec 14. Toxicol Pathol. 2011. PMID: 21378208

10

Revised guides for organ sampling and trimming in rats and mice--Part 3. A joint publication of the RITA and NACAD groups.

Morawietz G, Ruehl-Fehlert C, Kittel B, Bube A, Keane K, Halm S, Heuser A, Hellmann J; RITA Group; NACAD Group. Morawietz G, et al. Exp Toxicol Pathol. 2004 Jul;55(6):433-49. doi: 10.1078/0940-2993-00350. Exp Toxicol Pathol. 2004. PMID: 15384249

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