Hayes TR - Search Results

1

Radiosynthesis of O-(1-[¹⁸ F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin.

Hayes TR, Thompson CM, Blecha JE, Gerdes JM, VanBrocklin HF. Hayes TR, et al. J Labelled Comp Radiopharm. 2018 Dec;61(14):1089-1094. doi: 10.1002/jlcr.3688. Epub 2018 Nov 4. J Labelled Comp Radiopharm. 2018. PMID: 30347484 Free PMC article.

2

Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[¹⁸ F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [¹⁸ F]-VXS.

Hayes TR, Blecha JE, Chao CK, Huynh TL, VanBrocklin HF, Zinn KR, Taylor PW, Gerdes JM, Thompson CM. Hayes TR, et al. Ann N Y Acad Sci. 2020 Nov;1479(1):180-195. doi: 10.1111/nyas.14363. Epub 2020 May 20. Ann N Y Acad Sci. 2020. PMID: 32436233 Free PMC article.

3

Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats.

Hayes TR, Chao CK, Blecha JE, Huynh TL, Zinn KR, Thompson CM, Gerdes JM, VanBrocklin HF. Hayes TR, et al. Chem Res Toxicol. 2021 Jan 18;34(1):63-69. doi: 10.1021/acs.chemrestox.0c00237. Epub 2020 Dec 29. Chem Res Toxicol. 2021. PMID: 33373198 Free PMC article.

4

Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [¹¹C]2-Pyridinealdoxime Methiodide ([¹¹C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.

Neumann KD, Blecha JE, Hayes TR, Huynh T, Chao CK, Guilloteau N, Zinn KR, VanBrocklin HF, Thompson CM, Gerdes JM. Neumann KD, et al. Among authors: hayes tr. ACS Chem Neurosci. 2018 Dec 19;9(12):3007-3014. doi: 10.1021/acschemneuro.8b00212. Epub 2018 Aug 20. ACS Chem Neurosci. 2018. PMID: 30071719 Free PMC article.

5

Evaluating Radioactive Analogs of Doxorubicin to Quantify ChemoFilter Binding and Whole-Body Positron Emission Tomography/Magnetic Resonance Imaging for Drug Biodistribution.

Kumar P, Yee C, Blecha JE, Hayes TR, Kilbride BF, Stillson C, Losey AD, Mastria E, Jordan CD, Huynh TL, Moore T, Wilson MW, VanBrocklin HF, Hetts SW. Kumar P, et al. Among authors: hayes tr. J Vasc Interv Radiol. 2022 Jun;33(6):687-694. doi: 10.1016/j.jvir.2022.03.007. Epub 2022 Mar 15. J Vasc Interv Radiol. 2022. PMID: 35301127 Free PMC article.

6

Divergent synthesis of organophosphate [¹¹C]VX- and [¹¹C]Sarin-surrogates from a common set of starting materials.

Hayes TR, Blecha JE, Thompson CM, Gerdes JM, VanBrocklin HF. Hayes TR, et al. Appl Radiat Isot. 2019 Sep;151:182-186. doi: 10.1016/j.apradiso.2019.05.033. Epub 2019 May 24. Appl Radiat Isot. 2019. PMID: 31202183 Free PMC article.

7

Synthesis and Initial Biological Evaluation of Boron-Containing Prostate-Specific Membrane Antigen Ligands for Treatment of Prostate Cancer Using Boron Neutron Capture Therapy.

Wang S, Blaha C, Santos R, Huynh T, Hayes TR, Beckford-Vera DR, Blecha JE, Hong AS, Fogarty M, Hope TA, Raleigh DR, Wilson DM, Evans MJ, VanBrocklin HF, Ozawa T, Flavell RR. Wang S, et al. Among authors: hayes tr. Mol Pharm. 2019 Sep 3;16(9):3831-3841. doi: 10.1021/acs.molpharmaceut.9b00464. Epub 2019 Aug 16. Mol Pharm. 2019. PMID: 31381351 Free PMC article.

8

Amino Acid-Derived Sensors for Specific Zn²⁺ Detection Using Hyperpolarized ¹³ C Magnetic Resonance Spectroscopy.

Wang S, Korenchan DE, Perez PM, Taglang C, Hayes TR, Sriram R, Bok R, Hong AS, Wu Y, Li H, Wang Z, Kurhanewicz J, Wilson DM, Flavell RR. Wang S, et al. Among authors: hayes tr. Chemistry. 2019 Sep 12;25(51):11842-11846. doi: 10.1002/chem.201902771. Epub 2019 Aug 20. Chemistry. 2019. PMID: 31338914 Free PMC article.

9

99mTc-labeled cystine knot peptide targeting integrin αvβ6 for tumor SPECT imaging.

Zhu X, Li J, Hong Y, Kimura RH, Ma X, Liu H, Qin C, Hu X, Hayes TR, Benny P, Gambhir SS, Cheng Z. Zhu X, et al. Among authors: hayes tr. Mol Pharm. 2014 Apr 7;11(4):1208-17. doi: 10.1021/mp400683q. Epub 2014 Feb 24. Mol Pharm. 2014. PMID: 24524409 Free PMC article.

10

Isothiocyanate-Functionalized Bifunctional Chelates and fac-[M(I)(CO)3](+) (M = Re, (99m)Tc) Complexes for Targeting uPAR in Prostate Cancer.

Kasten BB, Ma X, Cheng K, Bu L, Slocumb WS, Hayes TR, Trabue S, Cheng Z, Benny PD. Kasten BB, et al. Among authors: hayes tr. Bioconjug Chem. 2016 Jan 20;27(1):130-42. doi: 10.1021/acs.bioconjchem.5b00531. Epub 2015 Dec 30. Bioconjug Chem. 2016. PMID: 26603218 Free PMC article.

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