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Page 1
Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.
Villa F, Carrizzo A, Spinelli CC, Ferrario A, Malovini A, Maciąg A, Damato A, Auricchio A, Spinetti G, Sangalli E, Dang Z, Madonna M, Ambrosio M, Sitia L, Bigini P, Calì G, Schreiber S, Perls T, Fucile S, Mulas F, Nebel A, Bellazzi R, Madeddu P, Vecchione C, Puca AA. Villa F, et al. Among authors: damato a. Circ Res. 2015 Jul 31;117(4):333-45. doi: 10.1161/CIRCRESAHA.117.305875. Epub 2015 Jun 1. Circ Res. 2015. PMID: 26034043 Free PMC article.
A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA. Vecchione C, et al. Among authors: damato a. Sci Rep. 2017 Aug 29;7(1):9706. doi: 10.1038/s41598-017-10341-x. Sci Rep. 2017. PMID: 28852218 Free PMC article.
Single systemic transfer of a human gene associated with exceptional longevity halts the progression of atherosclerosis and inflammation in ApoE knockout mice through a CXCR4-mediated mechanism.
Puca AA, Carrizzo A, Spinelli C, Damato A, Ambrosio M, Villa F, Ferrario A, Maciag A, Fornai F, Lenzi P, Valenti V, di Nonno F, Accarino G, Madonna M, Forte M, Calì G, Baragetti A, Norata GD, Catapano AL, Cattaneo M, Izzo R, Trimarco V, Montella F, Versaci F, Auricchio A, Frati G, Sciarretta S, Madeddu P, Ciaglia E, Vecchione C. Puca AA, et al. Among authors: damato a. Eur Heart J. 2020 Jul 7;41(26):2487-2497. doi: 10.1093/eurheartj/ehz459. Eur Heart J. 2020. PMID: 31289820 Free PMC article.
LAV-BPIFB4 associates with reduced frailty in humans and its transfer prevents frailty progression in old mice.
Malavolta M, Dato S, Villa F, Rango F, Iannone F, Ferrario A, Maciag A, Ciaglia E, D'amato A, Carrizzo A, Basso A, Orlando F, Provinciali M, Madeddu P, Passarino G, Vecchione C, Rose G, Puca AA. Malavolta M, et al. Aging (Albany NY). 2019 Aug 28;11(16):6555-6568. doi: 10.18632/aging.102209. Epub 2019 Aug 28. Aging (Albany NY). 2019. PMID: 31461407 Free PMC article.
Transfer of a human gene variant associated with exceptional longevity improves cardiac function in obese type 2 diabetic mice through induction of the SDF-1/CXCR4 signalling pathway.
Dang Z, Avolio E, Thomas AC, Faulkner A, Beltrami AP, Cervellin C, Carrizzo A, Maciag A, Gu Y, Ciaglia E, Finato N, Damato A, Spinetti G, Alenzi A, Paisey SJ, Vecchione C, Puca AA, Madeddu P. Dang Z, et al. Among authors: damato a. Eur J Heart Fail. 2020 Sep;22(9):1568-1581. doi: 10.1002/ejhf.1840. Epub 2020 May 8. Eur J Heart Fail. 2020. PMID: 32384208 Free PMC article.
The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease.
Di Pardo A, Ciaglia E, Cattaneo M, Maciag A, Montella F, Lopardo V, Ferrario A, Villa F, Madonna M, Amico E, Carrizzo A, Damato A, Pepe G, Marracino F, Auricchio A, Vecchione C, Maglione V, Puca AA. Di Pardo A, et al. Among authors: damato a. Cell Death Dis. 2020 Jul 18;11(7):546. doi: 10.1038/s41419-020-02754-w. Cell Death Dis. 2020. PMID: 32683420 Free PMC article.
LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism.
Spinelli CC, Carrizzo A, Ferrario A, Villa F, Damato A, Ambrosio M, Madonna M, Frati G, Fucile S, Sciaccaluga M, Capunzo M, Calì G, Milanesi L, Maciag A, Puca AA, Vecchione C. Spinelli CC, et al. Among authors: damato a. Cardiovasc Res. 2017 Jun 1;113(7):795-804. doi: 10.1093/cvr/cvx072. Cardiovasc Res. 2017. PMID: 28419216 Free PMC article.
The Impact of Aging on Cardio and Cerebrovascular Diseases.
Izzo C, Carrizzo A, Alfano A, Virtuoso N, Capunzo M, Calabrese M, De Simone E, Sciarretta S, Frati G, Oliveti M, Damato A, Ambrosio M, De Caro F, Remondelli P, Vecchione C. Izzo C, et al. Among authors: damato a. Int J Mol Sci. 2018 Feb 6;19(2):481. doi: 10.3390/ijms19020481. Int J Mol Sci. 2018. PMID: 29415476 Free PMC article. Review.
Author Correction: A rare genetic variant of BPIFB4 predisposes to high blood pressure via impairment of nitric oxide signaling.
Vecchione C, Villa F, Carrizzo A, Spinelli CC, Damato A, Ambrosio M, Ferrario A, Madonna M, Uccellatore A, Lupini S, Maciag A, Ryskalin L, Milanesi L, Frati G, Sciarretta S, Bellazzi R, Genovese S, Ceriello A, Auricchio A, Malovini A, Puca AA. Vecchione C, et al. Among authors: damato a. Sci Rep. 2019 Jun 28;9(1):9574. doi: 10.1038/s41598-019-45691-1. Sci Rep. 2019. PMID: 31249326 Free PMC article.
650 results